shRNA

Overview

The shRNA Core Facility was closed in November 2016. The College has decided to leverage the overlapping expertise present in current cores and redistribute the major services of the shRNA Core to other existing facilities at Einstein. See below for details.

Services

CRISPR-Cas9 services for cell lines will now be performed in the Gene Modification Facility. The Gene Modification Facility already offers CRISPR services for genetic modification of mice and will utilize this scientific expertise to provide CRISPR services for the gene modification of cell lines as well. You can access these services through the core's site in iLab.

The human and mouse whole genome shRNA library has been relocated to the Molecular Cytogenetic Core. The core staff will pull requested shRNA and ORF clones from our collection for investigators. You can access this service through the core's site in iLab.

Access and operation of the Operetta instrument for high-content imaging will now be coordinated through the Macromolecular Therapeutics Development Facility (MTDF). You can access this service through the core's site in iLab.

Lentivirus prep from shRNA and CRSPR constructs can be obtained from our Gene Therapy Core from clones obtained from the Molecular Cytogenetic Core. You can access this service through the core's site in iLab.

 

Location and Contacts

See info above