X-Ray Crystallography

Overview

The X-Ray Crystallography Facility provides the expertise needed to obtain high-resolution structures by X-ray diffraction, including crystallization, primary phasing, structure refinement and data interpretation. To rapidly accomplish these tasks, the facility is equipped with state-of-the-art robotics for screening sub-microliter volumes of protein and RT-PCR based stability tests to enhance crystallization efforts. All data are collected using synchrotron radiation using our rapid and sustained access to beamlines at Brookhaven National Labs. These structural technologies are complemented by cryo-electron microscopy, electron paramagnetic resonance, a wide range of vibrational spectroscopies, novel macromolecular footprinting approaches and computational biology. A full list of services is available on the facility website.

Services

  • Support for solving structures using X-ray crystallography:
    • Data collection, processing and interpretation
    • Structure solution
    • Structure analysis

Location and Contacts

X-Ray Crystallography

Ullmann 413

 
 
 

Scientific Director
Steven C. Almo, Ph.D.
718.430.2746
steve.almo@einstein.yu.edu

Associate Director
Vladimir Malashkevich, Ph.D.
718.430.2949
vladimir.malashkevich@einstein.yu.edu