Research Profiles

Scientific Discovery

John M. Greally, M.B.,B.Ch., Ph.D.

Gene Expression: Turning Diseases On & Off

John Greally, M.B., B.Ch., Ph.D., is a leader in the field of epigenomics, which involves the study of chemicals that attach to genes and affect their expression. Dr. Greally’s research has led to a better understanding of the epigenetic regulation of stem cells and of the epigenetic abnormalities that underlie human diseases including breast cancer, diabetes, Huntington’s disease, autism and allergies. Since epigenetic changes are reversible, his work in identifying epigenetic abnormalities could lead to novel therapies for these conditions. Dr. Greally is professor of genetics, of medicine (hematology), and of pediatrics, and the Faculty Scholar for Epigenomics.

 
 
 

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