Job Title:
Postdoctoral Position in Orphan Receptors in Drug Metabolism
Job Description:
PXR, an adopted orphan receptor, is a key mediator of gene expression that controls drug (xenobiotic) metabolism and carcinogenesis. Aberrant activation of PXR results in unpredictable drug levels and toxicities. Research focuses on defining the mechanism of action of drug inhibitors to an orphan receptor, PXR. The methodologies involve use of functional gene expression assays, proteomics and genetic screens for identification of binding targets on PXR.
Applicants required to have a Ph.D., or M.D./Ph.D., with expertise in molecular biology and, preferably, yeast assays. Please send CV and names and contact information of three references to:
Sridhar Mani, MD
Department of Medicine/Cancer Center
Albert Einstein College of Medicine
Jack and Pearl Resnick Campus
1300 Morris Park Avenue
Bronx, NY 10461
EOE
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