Einstein Experts

Tuberculosis (TB)

William R. Jacobs, Jr., Ph.D.

William R. Jacobs, Jr., Ph.D.

Professor, Microbiology & Immunology, Einstein

Professor, Genetics, Einstein

Investigator, Howard Hughes Medical Institute (HHMI)

Infectious diseasesTuberculosis (TB)Vaccines

Molecular genetics

Dr. Jacobs is pioneering the use of molecular genetics to control tuberculosis (TB), which kills nearly two million people a year. His research is identifying the genes that make Mycobacterium  tuberculosis (MTB) - the bacteria that causes TB -  virulent, identifying new drug targets and engineering weakened strains that can be used as live vaccines. Dr. Jacobs was the first scientist to introduce foreign DNA into MTB, a technique now regularly used by TB investigators around the world. read more...