Professor, Microbiology & Immunology, Einstein
Professor, Genetics, Einstein
Leo and Julia Forchheimer Chair in Microbiology & Immunology, Einstein
Investigator, Howard Hughes Medical Institute (HHMI)
Infectious diseasesTuberculosis (TB)Vaccines
Dr. Jacobs is pioneering the use of molecular genetics to control tuberculosis (TB), which kills nearly two million people a year. His research is identifying the genes that make Mycobacterium tuberculosis (MTB) - the bacteria that causes TB - virulent, identifying new drug targets and engineering weakened strains that can be used as live vaccines. Dr. Jacobs was the first scientist to introduce foreign DNA into MTB, a technique now regularly used by TB investigators around the world. read more...
Professor and Chair, Microbiology & Immunology
Professor, Medicine (Rheumatology)
Murray and Evelyne Weinstock Chair in Microbiology & Immunology
Microbiology & ImmunologyT-cell immunityTuberculosis (TB)
Dr. Porcelli studies the control of acquired immunity – the type that develops when our bodies generate specific responses involving antibodies or T cells following exposure to vaccines or infection by disease-causing microbes. In particular, he investigates how T cells – which supervise both defense against microbes and immune tolerance – control the acquired immune response. read more...