Harold and Muriel Block Chair in Epidemiology & Population Health
Division Head, Division of Biostatistics, Department of Epidemiology & Population Health
Director of the Biostatistics, Epidemiology and Research Design Core of the Institute for Clinical and Translational Research
Director, Quantitative Sciences in Biomedical Research Center
Dr. Kim’s research focuses on statistical methods for designing and analyzing clinical trials and epidemiologic studies (research of the factors affecting health and illness). Most clinical trials aim to demonstrate superiority of an experimental treatment relative to a standard treatment or placebo. An increasing number of trials, however, seek to show that the effects of two treatments on a particular outcome are equivalent, or that one treatment is not inferior to another. These goals are of interest when the new therapy offers benefits such as reduced cost, toxicity, or invasiveness. Dr. Kim is investigating the effects of non-compliance, outcome misclassification and measurement error on equivalence and non-inferiority trials and developing new approaches for defining the non-inferiority margin. Her research interests also include the development of methods for analyzing multivariate and interval-censored survival data. In addition, she collaborates on studies in cancer, rheumatology, and HIV/AIDS.
Dr. Kim has been head of the Division of Biostatistics since 2003, is Director of the Biostatistics Shared Resource of the Institute of Clinical and Translational Research,and Director of the Center for Quantitative Sciences. She is a Fellow of the American Statistical Association, on the American Statistical Association Council of Chapters Governing Board, and is a member of the Medical and Scientific Advisory Council of the Lupus Foundation of America. She has participated on numerous grant review panels for the National Institutes of Health and is currently a member of the NIH Arthritis, Musculoskeletal and Skin Diseases Clinical Trials Review Committee.
Petri, M., Kim, M., Kalunian, K., et al. Combined oral contraceptives are not associated with an increased rate of flare in SLE patients in the SELENA Trial. New England Journal of Medicine 2005; 353:2550 - 2558.
Ginzler, E., Dooley, M., Aranow, C., Kim, M., et al. Comparison of mycophenolate mofetil to intravenous cyclophosphamide for induction therapy of severe active lupus nephritis. New England Journal of Medicine 2005; 353: 2219 - 2228.
Buyon, J., Petri, M., Kim, M., et al. . Estrogen/Cyclic progesterone replacement is associated with an increased rate of mild/moderate but not severe flares in SLE: The SELENA Trial. Annals of Internal Medicine 2005; 953 - 962.
Sheng, D. and Kim, M.Y. The effects of non-compliance on intent-to-treat analysis of equivalence trials. Statistics in Medicine 2006; 25:1183-1199.
Kim, M.Y., Xue, X., Du, E. Approaches for calculating power for case-cohort studies. Biometrics 2006; 62: 929-922.
Xue, X., Kim, M., and Shore, R. Cox regression analysis in presence of collinearity: an application to assessment of health risks associated with occupational radiation exposure. Lifetime Data Analysis 2007; 13:333-350.
Kabat, G., Kim, M., Hunt, S., Chlebowski, R., Rohan, T. Body mass index and waist circumference in relation to lung cancer risk in the Women's Health Initiative. American Journal of Epidemiology 2008; 168:158-169.
Kim, M.Y. Using the instrumental variables estimator to analyze non-inferiority trials with non-compliance. Journal of Biopharmaceutical Statistics 2010; 20:745-758.
Heo, M., Kim, Y., Xue, X., Kim, M. Sample size requirement to detect an intervention effect at the end of follow-up in a longitudinal cluster randomized trial. Statistics in Medicine 2010; 29:382-290.
Izmirly, P., Chalumeau, N., Pisoni, C., Khamashta, M., Kim, M., Saxena, A., Friedman, D., Llanos, C., Piette, J., Buyon, J., Maternal use of hydroxychloroquine is associated with a reduced risk of recurrent anti-SSA/Ro-associated cardiac manifestations of neonatal lupus. Circulation 2012; 126:76-82
Xie, X., Xue, X., Gange, S., Strickler, H., Kim, M., and the WIHS HPV Study Group. Estimationand inference on correlations between biomarkers with repeated measures and left-censoring dueto minimum detection levels. Statistics in Medicine 2012; 31:2275-2289
Xue, X., Kim, M., Gaudet, M., Park, Y., Heo, M., Hollenbeck, A., Strickler, H., Gunter, M. A Comparison of the Polytomous Logistic Regression and Joint Cox Proportional Hazards Models for Evaluating Multiple Disease Subtypes in Prospective Cohort Studies. Cancer Epidemiology, Biomarkers, and Prevention 2013; 22:275-285.
Wang, C., Hall, C., Kim, M. A comparison of power analysis methods for evaluating the effects of a predictor on slopes in longitudinal designs with missing data. Statistical Methods in Medical Research (in press).
More Information About Dr. Mimi Kim
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Albert Einstein College of Medicine
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