Michael V. L. Bennett, D.Phil.

Electrical synapses, gap junctions and hemichannels

Garre, J.M., Bennett, M.V.L. Gap junctions and electrical synapses. In: The Sticky Synapse: Cell Adhesion Molecules and Their Role in Synapse Formation and Maintenance, Eds: Hortsch, M.; Umemori, H.; Springer, 2009, pp. 423 ¨C 440. 332.

Orellana, J.A., Hern¨¢ndez, D.E., Ezan, P., Velarde, V., Bennett, M.V.L., Giaume, C., S¨¢ez, J.C. Hypoxia in high glucose followed by reoxygenation in normal glucose reduces the viability of cortical astrocytes through increased permeability of connexin 43 hemichannels. Glia, 58: 329 ¨C 343, 2010.

Bennett, M.V.L. Gap junctions and electrical synapses. In: Squire LR (ed.) Encyclopedia of Neuroscience, vol. 4, pp. 529-548, Oxford, Academic Press, 2009.

Orellana, J.A., S¨¢ez, P.J., Shoji, K.F., Schalper, K.A., Palacios-Prado, N., Velarde, V., Giaume, C., Bennett, M.V.L., S¨¢ez, J.C. Modulation of brain hemichannels and gap junction channels by pro-inflammatory agents and their possible role in neurodegeneration. Antioxidants & Redox Signaling, 11: 369-399, 2009.

Flores, C.E., Li, X., Bennett, M.V.L., Nagy, J.I., Pereda, A.E. Interaction between connexin35 and zonula occludens-1 and its potential role in the regulation of electrical synapses. Proc. Natl. Acad. Sci. USA, 105: 12545-1250, 2008.

Retamal, M.A., Schalper, K.A., Shoji, K.F., Bennett, M.V.L., S¨¢ez, J.C. Opening of connexin 43 hemichannels is increased by lowering intracellular redox potential. Proc. Natl. Acad. Sci. USA, 104: 8322-8327, 2007.

Retamal, M.A., Schalper, K.A., Shoji, K.F., Orellana, J.A., Bennett, M.V.L., Saez, J.C. Possible involvement of different connexin43 domains in plasma membrane permeabilization induced by ischemia-reperfusion. J. Membr. Biol., 218: 49-63, 2007.

Bennett, M.V.L., Pereda, A. Pyramid power: Principal cells of the hippocampus unite! Brain Cell Biololgy, 35: 5-11, 2006.

Abrams, C.K., Freidin, M.M., Verselis, V.K., Bargiello, T.A., Kelsell, D.P., Richard, G., Bennett, M.V.L., Bukauskas, F.F. Properties of human connexin 31, which is implicated in hereditary dermatological disease and deafness. Proc. Natl. Acad. Sci. USA, 103: 5213-5218, 2006.

Bukauskas, F.F., Kreuzberg, M.M., Rackauskas, M., Bukauskiene, A., Bennett, M.V.L., Verselis, V.K., Willecke, K. Properties of mouse connexin 30.2 and human connexin 31.9 hemichannels: Implications for atrioventricular conduction in the heart. Proc. Natl. Acad. Sci. USA, 103: 9726-9731, 2006.

NMDA receptors

Lau, C.G., Takayasu, Y., Rodenas-Ruano, A., Paternain, A.V., Lerma, J., Bennett, M.V.L., Zukin, R.S. SNAP-25 is a target of PKC phosphorylation critical to NMDA receptor trafficking. J. Neurosci. 30: 242-254, 2009.

Lau, C.G., Takeuchi, K., Rodenas-Ruano, A., Takayasu, Y., Murphy, J., Bennett, M.V.L., Zukin, R.S. Regulation of NMDA receptor Ca²⁺ signalling and synaptic plasticity. Biochem. Soc. Trans. 37: 1369 - 74, 2009.

Yang, Y., Takeuchi, K., Rodenas-Ruano, A., Takayasu, Y., Bennett, M.V.L., Zukin, R.S. Developmental switch in
requirement for PKA RIIbeta in NMDA-receptor-dependent synaptic plasticity at Schaffer collateral to CA1 pyramidal cell synapses. Neuropharmacology, 56: 56-65, 2009.

Skeberdis, V.A., Chevaleyre, V., Lau, C.G., Goldberg, J.H., Pettit, D.L., Suadicani, S.O., Lin, Y., Bennett, M.V.L., Yuste, R., Castillo, P.E., Zukin, R.S. Protein kinase A regulates calcium permeability of NMDA receptors. Nat. Neurosci. 9: 501-510, 2006.

Lin, Y., Jover-Mengual, T., Wong, J., Bennett, M.V.L., Zukin, R.S. PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating. Proc. Natl. Acad. Sci. USA, 103: 19902-19907, 2006.

Global ischemia, delayed neurodegeneration

Stetler, R.A., Gao, Y., Zukin, R.S., Vosler, P.S., Zhang, L., Zhang, F., Cao, G., Bennett, M.V.L., Chen, J. Apurinic/apyrimidinic endonuclease APE1 is required for PACAP-induced neuroprotection against global cerebral ischemia. Proc. Natl. Acad. Sci. USA. 107: 3204 - 9, 2010.

Miyawaki, T., Mashiko, T., Ofengeim, D., Flannery, R.J., Noh, K.-M., Bonanni, L., Bennett, M.V.L., Zukin, R.S., Jonas, E.A. Ischemic preconditioning blocks mitochondrial translocation of BAD and cleavage of Bcl-xL in CA1 neurons after severe ischemic insult. Proc. Natl. Acad. Sci. USA, 105: 4892-4897, 2008.

Formisano, L., Noh, K.M., Miyawaki, T., Mashiko, T., Bennett, M.V.L., Zukin, R.S. Ischemic insults promote epigenetic reprogramming of ¦Ì opioid receptors in hippocampal neurons. Proc. Natl. Acad. Sci. USA, 104: 4170-4175, 2007.