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Faculty Profile

Solomon L. Moshe, M.D.

Dr. Solomon L. Moshe

Professor, The Saul R. Korey Department of Neurology

Professor, Department of Pediatrics

Professor, Dominick P. Purpura Department of Neuroscience

Director, Division of Neurology, Department of Pediatrics

Director, Clinical Neurophysiology, The Saul R. Korey Department of Neurology

Charles Frost Chair in Neurosurgery and Neurology

Director, Division of Pediatric Neurology, The Saul R. Korey Department of Neurology

 

Professional Interests

Since 1979, Dr. Mosh�s research has focused on translational approaches to understand the mechanisms underlying the development of epilepsy and its consequences in infants and children. His laboratory has developed and patented an animal model that replicates human infantile spasms, which can be used to identify novel treatments of this devastating condition. His work has identified an endogenous brain circuit that can control the expression of seizures as a function of age and gender. In addition to his laboratory research, he is actively involved in several large, multi-center studies examining the outcomes of prolonged, febrile seizures (seizures occurring with fever) and absence epilepsy to identify predictive biomarkers of the course and response to treatment. In more than 20 years, Dr. Mosh� has mentored numerous scientists and clinicians from around the world in clinical epilepsy and basic science epilepsy-related research.

Dr. Mosh� is active in numerous professional societies and elected President of the American Epilepsy Society, the American Clinical Neurophysiology Society, the Eastern Association of Electroencephalographers, , and is the current President of The International League against Epilepsy. He is an elected member of the American Neurological Association and the American Pediatric Society.

 

Selected Publications

Moshé, S.L., Perucca, E.,Wiebe, S., Mathern, G.W. The International League Against Epilepsy at the Threshold of its second century:  Year 1. Epilepsia 52:185-197 (2011).

 Ono, T., Moshé, S.L., Galanopoulou, A.S. Carisbamate acutely suppresses spasms in a rat model of symptomatic infantile spasms in a rat model of symptomatic infantile spasms.  Epilepsia 152:1678-1684 (2011).

  Ono, T., Moshé, S.L. Can epilepsy be prevented?  Neurol. Asia 16:1-3 (2011).

Fried, S., Moshé, S.L. Basic physiology of the EEG. Neurol. Asia 16:23-25 (2011).

 Beal, J.C., Sogawa, Y., Ceresnak, S.R., Mahgerefteh, J., Moshé, S.L. Late onset ictal asystole in refractory epilepsy.  Pediatric Neurol. 45:253-255 (2011).

 Yozawitz, E.G., Scantlebury, M.H., Robinson, J., Jehle, R., Moshé, S.L. Recurrence of childhood absence epilepsy as pyknolepsy in adolescence. Epileptic Disorders 13:313-6 (2011).

 Galanopoulou, A.S., Moshé, S.L. In search of epilepsy biomarkers in the immature brain: goals, challenges, strategies. Biomarkers Medicine 5:615-628 (2011).

 Moshe, S.L. In support of the ILAE Commission classification proposal. Epilepsia 52:1200-1 (2012).

 Arida, R.M., Scorza, F.A., Cavalheiro, E.A., Perucca, E., Moshé, S.L. Can people with epilepsy enjoy sports? Epilepsy Res. 98:94-95 (2012).

 Moshé, S.L., Perucca, E., Wiebe, S., Mathern, G.W. The International League Against Epilepsy at the Threshold of its second century: Year 2.  Epilepsia 53:215-219 (2012).

 Galanopoulou, A.S., Buckmaster, P.S., Staley, K., Moshé, S.L., Perucca, E., Engel, J., et al. Identification of new epilepsy treatments:  Issues in preclinical methodology. Epilepsia 53:571-82 (2012).

 Gulcebi, M.I., Ketenci, S., Linke, R., Hacioglu, H., Yanali, H., Veliskova, J., Moshe, SL, Onat, F., Cavdar, S. Topographical connections of the substantia nigra pars reticulate to higher-order thalamic nuclei in the rat.  Brain Res. Bull 87:312-18 (2012).

 Cameron, A., Bansal, A., Dua, T., Hill, S., Moshé, Mantel-Teeuwisse, A., Saxena, S. Mapping the availability, price and affordability of antiepileptic medicines in 46 countries.  Epilepsia 53:962-69 (2012).

 Avanzini, G., Manganotti, P., Meletti, S., Moshé, S.L., Panzica, F., Wolf, P., Capovilla, G. The system epilepsies: A pathophysiological hypothesis.  Epilepsia 53:771-778 (2012).

 Shinnar, S., Bello, J.A., Chan, S., Hesdorffer, D., Lewis, D.V., MacFall, J.R., Pellock, J.M., Nordli, D.R. Moshe, S.L., et al. MR Imaging abnormalities following febrile status epilepticus in children: The FEBSTAT Study. Neurology (2012) In Press.

 Epstein, L., Shinnar, S., Hesdorffer, D.C., Nordli, D., Hamidullah, A., Benn, E., Pellock, J., Frank, M., Lewis, D., Moshe, S.L., Shinnar, R.C., Sun, S. Human Herpes virus 6 and 7 in Febrile Status Epilepticus: The FEBSTAT study. Epilepsia 1-8 (2012).

 Hesdorffer, D., Shinnar, S., Lewis, D.V., Moshé, S.L., Nordli, D., Pellock, J.M., Macfall, J., Shinnar, R.C., Masur, D., Frank, L.M., Epstein, L.G., Litherland, C., Seinfeld, S.,  Bello, J., Chan, S., Bagiella, E., Sun, S. Design and Phenomenology of the FEBSTAT Study. Epilepsia 1-10 (2012).

 Nordli, DR., Moshé, S.L., Shinnar, S., Hesdorffer, D., Sogawa, Y., Pellock, J.M., Lewis, D.V., Frank, L.M., Shinnar, R.C., Sun, S.S. Acute EEG findings in children with febrile status epilepticus: Results of the FEBSTAT study. Neurology 2012, in press.

 

More Information About Dr. Solomon Moshe

Developmental Epilepsy Laboratory

Clinical Programs in Child Neurology and Neurophysiology at Montefiore Medical Center

Material in this section is provided by individual faculty members who are solely responsible for its accuracy and content.

Contact

Albert Einstein College of Medicine
Rose F. Kennedy Center
1410 Pelham Parkway South , Room 316
Bronx, NY 10461

Tel: 718.430.2447
solomon.moshe@einstein.yu.edu

 
Pubmed Search
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Media Coverage

WebMD interviews Dr. Solomon Moshé about a new study that found treatment-resistant epilepsy is linked to autism.

More media coverage