Faculty Profile

Dr. Sayan Nandi, Ph.D.

Sayan Nandi, Ph.D.

Research Assistant Professor, Department of Developmental & Molecular Biology

Areas of Research: Synaptic biology, microglial activation, neuroinflammation, neural mechanisms underlying learning and memory.

Professional Interests

My research goal is to understand how cellular communication is important for CNS homeostasis. In particular, I am interested in understanding how information is processed and encoded in the brain at cellular and circuit levels, leading up to complex behavioral computation. Roles for neuronal as well as for microglial activation in these homeostatic processes will be studied using various mouse models.

Selected Publications

Nandi, S., Alviña, K., Lituma, P.J., Castillo, P.E., Hébert, J.M. (2017). Neurotrophin and FGF signaling adapter proteins, FRS2 and FRS3 regulate dentate granule cell maturation and excitatory synaptogenesis. Neuroscience. (In press)

Nandi, S., Gutin, G., Blackwood, C.A., Kamatkar, N.G., Lee, K.W., Wang, F., Fishell, G., Goldfarb, M., Hébert, J.M. (2017). FGF-dependent, context-driven role for FRS adapters in the early telencephalon. Journal of Neuroscience. 37(23):5690-5698   

Nandi, S., Chandramohan, D., Fioriti, L., Melnick, A.M., Hébert, J.M., Mason, C.E., Rajasethupathy, P., Kandel, E.R. (2016). Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain. Proceedings of the National Academy of Sciences. 113(45):12697-12702

Nandi, S., Cioce, M., Yeung, Y.G., Nieves, E., Tesfa, L., Lin, H., Hsu, A.W., Halenbeck, R., Cheng, H.Y., Gokhan, S., Mehler, M.F., Stanley, E.R. (2013). Receptor-type protein tyrosine phosphatase zeta is a functional receptor for interleukin-34. The Journal of Biological Chemistry. 288(30):21972-86

Nandi, S., Gokhan, S., Dai, X.M., Wei, S., Enikolopov, G., Lin, H., Mehler, M.F., Stanley, E.R. (2012). The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation. Developmental Biology. 367(2):100-13

Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M.F., Conway, S.J., Ng, L.G., Stanley, E.R., Samokhvalov, I.M., Merad, M. (2010). Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science. 330(6005):841-5

Wei, S., Nandi, S., Chitu, V., Yeung, Y.G., Huang, M., Williams, L.T., Lin, H., Stanley, E.R. (2010). Functional overlap, but differential expression of CSF-1 and IL-34, in their CSF-1 receptor-mediated regulation of myeloid cells. Journal of Leukocyte Biology. 88(3):495-505

Nandi, S., Akhter, M.P., Seifert, M.F., Dai, X.M., Stanley, E.R. (2006). Developmental and functional significance of the CSF-1 proteoglycan chondroitin sulfate chain. Blood. 107(2): 786-95 

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Albert Einstein College of Medicine
Jack and Pearl Resnick Campus
1300 Morris Park Avenue
Chanin Building, Room 510
Bronx, NY 10461

Tel: 718.430.2315
Fax: 718.430.8567

Research Information