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Faculty Profile

Jeannette R. Mahoney, Ph.D.

Dr. Jeannette R. Mahoney
 

Professional Interests

Multisensory integration (MSI) is an integral aspect of functioning and mobility in everyday life and ability to function well in the real world requires intact MSI. MSI is not well understood in aging, and its relation to cognitive and motor function has not been fully evaluated. The main objective of my research is to investigate the behavioral, functional, and anatomical correlates of MSI in older adults and to determine whether MSI has associations with specific cognitive and motor outcomes. Funding from a pilot grant award that I received in 2009-2010 from AECOM's Resnick Gerontology Center provided a solid launching pad for my current research aims in MSI and aging. Studying the facilitative benefit of multisensory information processing in older adults could have important clinical and public health implications! These include potentially providing insight into the cognitive and physical attributes of the aging process, affording an understanding of the biological basis of aging, and subsequently aiding in the identification of opportunities to introduce cognitive and physical remediation to older adults. Although admittedly speculative at this point, we believe that optimizing integration of visual-somatosensory inputs may ultimately provide the framework for successful interventions that will reduce falls, improve mobility, and help maintain functional independence in older adults.
 

Selected Publications

Mahoney, J.R., Verghese, J., Dumas, K. & Holtzer, R. Visual-Somatosensory Integration is linked to Physical Activity Level in Older Adults. Multisensory Research, Accepted, 2015.

England, S., Verghese, J., Mahoney, J.R., Trantzas, K., & Holtzer, R. Three level rating of turns while walking, Gait and Posture, 41(1):300-3, 2015.  PMID: 25282258

Lee, S., Verghese, J., Holtzer, R., Mahoney, J.R., & Oh-Park, M. Trunk Sway during Walking among Older Adults: Norms and Correlation with Gait Velocity. Gait & Posture, 40(4):676-681, 2014. PMID: 25155693

Mahoney, J.R., Verghese, J., Holtzer, R. & Allali, G. The evolution of mild parkinsonian signs in aging. Journal of Neurology, 261(10):1922-1928, 2014. PMID: 25047763

Allali, G., Verghese, J. & Mahoney, J.R.  Contributions of Parkinsonian features to Gait in the Elderly. Age (Dordr), 36:9678, 2014. PMID: 24981115

Mahoney, J.R., Holtzer, R., Dumas, K., & Verghese, J. Visual-Somatosensory Integration & Balance: Evidence for Psychophysical Integrative Differences in Aging. Multisensory Research, 27(1): 17-42, 2014. PMID: 25102664

Mahoney, J.R., Verghese, J., Dumas, K., & Holtzer, R. Visual-Somatosensory Integration in Aging: Does Stimulus Location Really Matter? Visual Neuroscience, 31(3):275-83, 2014. PMID: 24698637

Holtzer, R., Epstein, N., Mahoney, J.R., Izzetoglu, M., & Blumen, H.M. Neuroimaging of Mobility in Aging: A Targeted Review. Journal of Gerontology, Medical Sciences, 69(11):1375-88, 2014. PMID: 24739495

Holtzer, R., Mahoney, J.R., Verghese, J. Intraindividual variability but not speed of processing or conflict resolution predicts performance differences in gait speed in older adults. Journal of Gerontology: Medical Sciences, 69(8): 980-986, 2014. PMID: 24285744

Shapiro, M, Mahoney, J.R., Peyser, D., Zingman, B. & Verghese, J.  Cognitive Reserve Protects Against Apathy in Individuals with Human Immunodeficiency Virus. Archives of Clinical Neuropsychology, 29(1):110-120, 2014. PMID: 24021844

Shapiro, M., Mahoney, J., Zingman, B, Pogge, D, & Verghese, J.  Apathy Correlates with Cognitive Performance, Functional Disability, and HIV RNA Plasma Levels in HIV-Positive Individuals. Journal of Clinical and Experimental Neuropsychology, 35(9):934-945, 2013. PMID: 24090038

Oh-Park, M., Holtzer, R., Mahoney, J., Wang, Raghavan, P. & Verghese, J. Motor dual-task effect on gait and task of upper limbs in older adults under specific task prioritization: pilot study.  Aging Clinical and Experimental Research, 25(1):99-106, 2013. PMID: 23740639

Parihar, R., Mahoney, J.R., & Verghese, J.  Relationship of Gait and Cognition in the Elderly.  Current Translational Geriatrics and Experimental Gerontology Reports, 2:167-173, 2013. PMID: 24349877

Mahoney, J.R., Verghese J, Dumas K, Wang C, Holtzer R. The effect of multisensory cues on attention in aging. Brain Res. 1472, 63-73, 2012. PMID: 22820295

Oh-Park, M., Holtzer, R., Mahoney, J., Wang, C., & Verghese, J.  Effect of treadmill training on specific gait parameters in older adults with frailty: case series. J Geriatr Phys Ther. 34(4), 184-188, 2011. PMID: PMC3226950

Mahoney, J.R., Li, P., Oh-Park, M., Verghese, J., & Holtzer, R. Multisensory Integration Across the Senses in Young and Old Adults. Brain Research, 426, 43-53, 2011. PMID: PMC3232048

Holtzer, R., Shuman, M., Mahoney, J., Lipton, R., & Verghese, J. Cognitive Fatigue Defined in the Context of Attention Networks. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn., 18, 108-128, 2011. PMID: PMC3058923

Holtzer,R., Mahoney, J.R., Izzetoglu,M., Izzetoglu,K., Onaral, B., & Verghese, J.  fNIRS Study of Walking and Walking While Talking in Young and Old Individuals. J Int Neuropsychol Soc., 16(5), 877-89, 2011. PMID: PMC3148759

Mahoney, J., Verghese, J. Goldin, Y., Lipton, R. & Holtzer, R.  Alerting, Orienting, and Executive Attention in Older Adults. J Int Neuropsychol Soc., 16(5), 877-889, 2010. PMID: PMC3134373

Verghese J., Mahoney J., Wang C., Ambrose A.F., & Holtzer, R. Effect of cognitive remediation on gait in sedentary seniors. J Gerontol A Biol Sci Med Sci.,65(12), 1338-1343, 2010. PMID: 20643703

Katz, R., De Sanctis, P., Mahoney, J.R., Sehatpour, P., Murphy, C., Gomez-Ramirez, M., Alexopoulos, G.A., & Foxe, J.J.  Cognitive Control in Late-Life Depression: Response inhibition deficits and dysfunction of the Anterior Cingulate Cortex. Am J Geriatr Psychiatry, 18(11), 1017-1025, 2010. PMID: 20808083

Sehatpour, P., Molholm, S., Schwartz, T.H., Mahoney, J.R., Mehta, A., Javitt, D., Stanton, P.K., & Foxe, J.J. A human intracranial study of long-range oscillatory coherence across a frontal-occipital-hippocampal brain network during visual object processing. Proc Natl Acad Sci U S A., 105(11), 4399-4404, 2008. PMID: PMC 2393806

Gomez-Ramirez, M., Higgins, B.A., Rycroft, J.A., Owen, G.N., Mahoney, J., Shpaner, M., &  Foxe, J.J. The deployment of intersensory selective attention: A high-density electrical mapping study of the effects of Theanine. Clin Neuropharmacol., 30 (1), 25-38, 2007. PMID: 17272967

Butler, P.D., Martinez, A., Foxe, J.J., Kim, D., Zemon, V., Silipo, G., Mahoney, J., Shpaner, M., Jalbrzikowski, M., &. Javitt, D. C.  Subcortical visual dysfunction in schizophrenia drives secondary cortical impairments. Brain, 130, 417-430, 2007. PMC2072909

 

More Information About Dr. Jeannette Mahoney

Neurology Division of Cognitive & Motor Aging

Saul R. Korey Department of Neurology

Material in this section is provided by individual faculty members who are solely responsible for its accuracy and content.

Contact

Albert Einstein College of Medicine
Louis and Dora Rousso Building
1165 Morris Park Avenue , Room 304
Bronx, NY 10461

Tel: 718.430.3809
Fax: 718.430.3829
jeannette.mahoney@einstein.yu.edu

 
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