Faculty Profile

Dr. Alexander Maslov, M.D.,  Ph.D.

Alexander Maslov, M.D., Ph.D.

Research Assistant Professor, Department of Genetics

Selected Publications

  1. Quispe-Tintaya W, Gorbacheva T, Lee M, Makhortov S, Popov VN, Vijg J, Maslov AY. Quantitative detection of low-abundance somatic structural variants in normal cells by high-throughput sequencing. Nat Methods. 2016 Jun 6. doi:10.1038/nmeth.3893. [Epub ahead of print] PubMed PMID: 27271197
  2. Maslov AY, Quispe-Tintaya W, Gorbacheva T, White RR, Vijg J. High-throughput sequencing in mutation detection: A new generation of genotoxicity tests? Mutat Res. 2015 Apr 20. pii: S0027-5107(15)00091-3. doi: 10.1016/j.mrfmmm.2015.03.014. Review. PubMed PMID: 25934519.
  3. White RR, Milholland B, de Bruin A, Curran S, Laberge RM, van Steeg H, Campisi J, Maslov AY, Vijg J. Controlled induction of DNA double-strand breaks in the mouse liver induces features of tissue ageing. Nat Commun. 2015 Apr 10;6:6790. doi: 10.1038/ncomms7790. PubMed PMID: 25858675.
  4. Gorbacheva T, Quispe-Tintaya W, Popov VN, Vijg J, Maslov AY. Improved transposon-based library preparation for the Ion Torrent platform. Biotechniques. 2015 Apr 1;58(4):200-2. doi: 10.2144/000114277. PubMed PMID: 25861933.
  5. Delio M, Patel K, Maslov A, Marion RW, McDonald TV, Cadoff EM, Golden A, Greally JM, Vijg J, Morrow B, Montagna C. Development of a Targeted Multi-Disorder High-Throughput Sequencing Assay for the Effective Identification of Disease-Causing Variants. PLoS One. 2015 Jul 27;10(7):e0133742. doi: 10.1371/journal.pone.0133742. eCollection 2015. PubMed PMID: 26214305; PubMed Central PMCID: PMC4516357.
  6. Quispe-Tintaya W, White RR, Popov VN, Vijg J, Maslov AY. Rapid mitochondrial DNA isolation method for direct sequencing. Methods Mol Biol. 2015;1264:89-95. doi: 10.1007/978-1-4939-2257-4_9. PubMed PMID: 25631006.
  7. Quispe-Tintaya W, White RR, Popov VN, Vijg J, Maslov AY. Fast mitochondrial DNA isolation from mammalian cells for next-generation sequencing. Biotechniques. 2013 Sep;55(3):133-6. doi: 10.2144/000114077. PMID: 24003945.
  8. Maslov AY, Ganapathi S, Westerhof M, Quispe W, White RR, Van Houten B, Reiling E, Dollé ME, van Steeg H, Hasty P, Hoeijmakers JH, Vijg J. DNA damage in normally and prematurely aged mice. Aging Cell. 2013 Mar 15. doi: 10.1111/acel.12071. PMID: 23496256
  9. Maslov AY, Lee M, Gundry M, Gravina S, Strogonova N, Tazearslan C, Bendebury A, Suh Y, Vijg J. 5-aza-2'-deoxycytidine-induced genome rearrangements are mediated by DNMT1. Oncogene. 2012 Dec 13;31(50):5172-9. PMID: 22349820
  10. Maslov AY, Metrikin M, Vijg J. A dual-activation, adenoviral-based system for the controlled induction of DNA double-strand breaks by the restriction endonuclease SacI. Biotechniques. 2009 Oct;47(4):847-54.  PMID: 19852768
  11. Maslov AY, Vijg J. Genome instability, cancer and aging. Biochim Biophys Acta. 2009 Oct;1790(10):963-9.  PMID: 19344750
  12. Vijg J, Maslov AY, Suh Y. Aging: a sirtuin shake-up? Cell. 2008 Nov 8;135(5):797-8.  PMID: 19041745
  13. Maslov AY, Bailey KJ, Mielnicki LM, Freeland AL, Sun X, Burhans WC, Pruitt SC. Stem/Progenitor cell-specific enhanced green fluorescent protein expression driven by the endogenous mcm2 promoter. Stem Cells. 2007 Jan;25(1):132-8.  PMID: 17008428
  14. Bailey KJ, Maslov AY*, Pruitt SC. Accumulation of mutations and somatic selection in aging neural stem/progenitor cells. Aging Cell. 2004 Dec;3(6):391-7. PMID: 15569356
  15. Pruitt SC, Bussman A, Maslov AY, Natoli TA, Heinaman R. Hox/Pbx and Brn binding sites mediate Pax3 expression in vitro and in vivo. Gene Expr Patterns. 2004 Oct;4(6):671-85.  PMID: 15465489
  16. Maslov AY, Barone TA, Plunkett RJ, Pruitt SC. Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice. J Neurosci. 2004 Feb 18;24(7):1726-33.  PMID: 14973255
  17. Pashkov A, Maslov A. Effect of chalone and antichalone on free radical processes in the rat liver. Biull Eksp Biol Med. 1998 Feb; 125(2): 224-6.  PMID: 9559144

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Research Information