Subhrajit Saha, Ph.D.

Research Overview:

Intestinal stem cell regeneration to repair radiation injury

Investigation of the crosstalk between the factors of stem cell niche that are responsible for intestinal stem cell regeneration in radiation injury model.

Unfolded Protein Response and chemoresistant tumor

Role of unfolded protein response in high intensity focused ultrasound (HIFU) treated tumor cells to induce endoplasmic reticular stress and cell death in chemo-resistant tumors. This would allow therapeutic ultrasound to be a chemosensitizer for the treatment of recurrent and resistant solid tumors.