Science at the heart of medicine

5012 Renal, Respiratory and Acid-Base Physiology

COURSE DESCRIPTION: This course will cover the basic principles of renal, respiratory and acid-base physiology from the whole animal to the cellular and molecular levels. It will focus on functional mechanisms and homeostatic regulatory processes that maintain the volume and composition of body flu-ids. Homeostatic mechanisms will be discussed in relationship to human pathophysiological conditions. The course is required for all first year MSTP students.

REQUIRED MATERIALS: Readings from textbooks, journal and review articles will be provided.

PREREQUISITES: Membrane Physiology & Transport in Block 1 is a prerequisite to this course. Students should have a year of undergraduate chemistry and biology and preferably physics.

STUDENT PREPARATION: Students should be familiar with fundamental membrane and epithelial transport processes, membrane potentials, fluid mechanics and hemodynamics. Students should know about the G-protein coupled receptor second messenger signaling pathways regulating intracellular cAMP, cGMP, protein kinase C and IP3.


UNIQUE TRAINING OFFERED IN THIS COURSE: The course has no overlap with any other graduate division course. It will provide the students with an understanding of the kidney and lung function and how their function is homeostatical-ly regulated to maintain the volume, composition and acid-base balance of body fluids.

STUDENT ASSESSMENTS: Students will be assessed on in class paper presentations, class participation and a take home essay and short answer exam.