Science at the heart of medicine

7005 Molecular Cell Biology

COURSE DESCRIPTION: This course will cover basic areas in cell biology with emphasis on selected topics of current interest. The three main areas will be intracellular protein transport, the nucleus, and the cytoskeleton. Topics include: membrane structure and biogenesis, functions of intracellular membranes and the signal hypothesis, protein trafficking and intracellular sorting, glycosylation, exocytosis, endocytosis and membrane fusion, nuclear structure and organization, nuclear transport, mRNA localization, self assembly of cytoskeletal structures, actin, microtubules, intermediate filaments, molecular motors, mitosis, cell junctions, extracellular matrix, cytoskeleton and signal transduction.

REQUIRED MATERIALS: "Lewin's CELLS" 2015, Third edition (ISBN: 978-1-284-02939-0); eds. G. Plopper, D. Sharp, and E. Sikorski; Jones and Bartlett Publishers; Sudbury, MA. http://go.jblearning.com/CELLS3e   Reading the relevant chapter(s) prior to the lecture is required and essential for understanding the lectures. Several copies are on closed reserve in the library. The cheapest source for the book is Amazon and the E-Book is available through the Einstein online library at: http://zc6sj2ch8l.search.serialssolutions.com/?V=1.0&N=100&tab=BOOKS&L=ZC6SJ2CH8L&S=AC_T_B&C=Lewin%27s+cells  

PREREQUISITES: This is a demanding course involving a substantial amount of reading and should only be taken by those first year students with a background in biochemistry and cell biology.

STUDENT PREPARATION: N/A

SUITABLE FOR 1ST YEAR STUDENTS: Yes

UNIQUE TRAINING OFFERED IN THIS COURSE: N/A

STUDENT ASSESSMENTS: 3 exams and 3 team based learning sessions

CREDIT HOURS: 5.0