Science at the heart of medicine

7008 Membrane Potential and Transport

COURSE DESCRIPTION: Thermodynamics is briefly reviewed with special emphasis on the concept of chemical potential and its relation to the Boltzman Distribution. The gradient of chemical potential is then introduced as the driving force in transport phenomena. With these concepts established, the problems of equilibria and transport across membranes are taken up. These include diffusion, Donnan equilibrium, diffusion potentials, membrane potentials, fixed charge membranes, electrical excitability, and the analysis of single-channel records.

REQUIRED MATERIALS: N/A

PREREQUISITES: Basic knowledge of calculus and elementary thermodynamics

STUDENT PREPARATION: None

SUITABLE FOR 1ST YEAR STUDENTS: Yes

UNIQUE TRAINING OFFERED IN THIS COURSE: See course description above

STUDENT ASSIGNMENTS: Problem sets, final oral exam

CREDIT HOURS: 2.0