COURSE DESCRIPTION: This course will provide students with a broad overview of basic immunology, while also delving deeply into cellular and molecular details in areas of central importance to this field. The course will consider both innate and adaptive immunity and include the structure and function of key receptors including immunoglobulins, T cell receptors and innate pattern recognition receptors. The mechanisms of antibody formation and molecular aspects of cellular immunity, including T and B cell interactions and lymphocyte memory formation, will be emphasized, and connections to modern biomedical science will be highlighted. These will include presentations and discussions on autoimmunity, immunity against major microbial pathogens (viruses, bacteria, parasites), transplantation and tumor immunology. The course will rely on multiple materials, including formal lectures (from >22 Einstein Faculty), Seminal papers discussion and Immunological methods/mouse model lectures (prepared by advanced postdoctoral fellows), Assigned reading (selected textbook chapters, cutting edge review articles and didactic videos), Data driven learning sessions (“Hands-on” data analysis and interpretation) and mandatory attendance to select seminars of the Microbiology and Immunology Department. Successful completion of the course will provide students with strong fundamental knowledge in basic immunology, and assist them in deepening their knowledge of current research and developments in modern immunology.
REQUIRED MATERIALS: Janeway's Immunobiology 9th edition Kenneth P. Murphy, ISBN 978-0-8153-45053-0 Published by Garland Science, Taylor & Francis Group, LLC ; computer access; internet access.
STUDENT PREPARATION: Gene expression; protein structure; cell structure and organization
SUITABLE FOR 1ST YEAR STUDENTS: Yes
UNIQUE TRAINING OFFERED IN THIS COURSE: : Immunology training is provided by this course and no other. The course will also cover methods used extensively in immunology research and applicable to other fields.
STUDENT ASSESSMENTS: Exams (Midterm, Final); Class and Discussion Participation, Basic Concept Homework
CREDIT HOURS: 4.0