COURSE DESCRIPTION: This course provides an introduction to Clinical Research. The student will learn how clinical research studies are designed, how to analyze and interpret statistical comparisons, and will develop skills in critically reading the clinical research literature. The course consists of 11 lectures and includes the following topics. Study Design I: The research question; observational studies; Study Design II: clinical trials and meta-analysis; Biostatistics I: descriptive and analytic statistics - univariate techniques; Biostatistics II: analytic statistics - multivariate techniques; Biostatistics III: survival analysis; outcomes research: assessing quality of medical care; Evaluation of diagnostic testing; Clinical prediction rules; Cost-effectiveness and decision analysis; Emerging challenges in research: genetic approaches to complex disease; Research ethics; Opportunities in clinical research. The course will culminate with a Final Exam.
REQUIRED MATERIALS: N/A
STUDENT PREPARATION: N/A
SUITABLE FOR 1ST YEAR STUDENTS: 1st or 2nd year graduate (PhD) or MSTP students interested in clinical/translational research, especially those considering the new PhD concentration in Clinical Investigation (PCI), are encouraged to register.
UNIQUE TRAINING OFFERED IN THIS COURSE: N/A
STUDENT ASSESSMENTS: Students must attend at least 9 of the 11 lectures and pass the Final Exam to receive a passing grade.
STUDENTS MUST FIRST REGISTER FOR THE COURSE AND THEN FILL OUT AN ADDITIONAL REGISTRATION FORM IN THE CLINICAL RESEARCH TRAINING OFFICE.
CREDIT HOURS: 2.0