Science at the heart of medicine

7018 Computational Biology of Proteins

COURSE DESCRIPTION: It is an introductory course to Protein Bioinformatics. We provide a systematic introduction to the major techniques, algorithms and tools used in Bioinformatics (for sequence alignments, classifications, secondary and tertiary structure predictions, modeling, sampling of conformations, energy functions, prediction of various functional and structural features of proteins, docking etc.).

REQUIRED MATERIALSNot required, but suggested: Computational Biochemistry and Biophysics, Marcel Dekker, New York, NY, ISBN 978-0824704551. M. Watanabe, B. Roux, A. MacKerell, and O. Becker; Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids by R. Durbin, S. R. Eddy, A. Krogh, G. Mitchison ISBN 978-0521629713; Bioinformatics: The Machine Learning Approach, Second Edition by: P. Baldi ISBN 978-0262025065; Protein Structure Prediction: A Practical Approach by MJE Sternberg 978-0199634965; From Protein Structure to Function with Bioinformatics. Ed. Daniel John Rigden, Publisher: Springer; 2009 edition ISBN-13: 978-1402090578. 

PREREQUISITES: No

STUDENT PREPARATION: Clear understanding of basic biochemical and biophysical concepts are expected. i.e. Biochemistry course in first Block is advised.

SUITABLE FOR 1ST YEAR STUDENTS: Yes

UNIQUE TRAINING OFFERED IN THIS COURSE: N/A

STUDENT ASSESSMENTS: A midterm and a final exam.

CREDIT HOURS: 2.0