Department of Pathology

Department Faculty

Tina M. Calderon, Ph.D.

Dr. Tina M. Calderon

Research Assistant Professor, Department of Pathology

 

Selected Publications

Eugenin, E.A., D'Aversa, T.G., Lopez, L., Calderon, T.M. and Berman, J.W.:  MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis.  J. Neurochem.  85:1299-1311, 2003.

Eugenin, E.A., Dyer, G., Calderon, T.M. and Berman, J.W.:  HIV-1 tat protein induces a migratory phenotype in human fetal microglia by a CCL2 (MCP-1)-dependent mechanism:  Possible role in NeuroAids.  Glia.  49:501-510, 2005.

Eugenin, E.A., Osiecki, K., Lopez, L., Goldstein, H., Calderon, T.M. and Berman, J.W.:  CCL2/monocyte chemoattractant protein-1 mediates enhanced transmigration of human immunodeficiency virus (HIV)-infected leukocytes across the blood-brain barrier:  a potential mechanism of HIV-CNS invasion and NeuroAIDS.  J. Neurosci. 26:1098-1106, 2006.

Eugenin, E.A., Gamss, R., Buckner, C., Buono, D., Klein, R.S., Schoenbaum, E.E., Calderon, T.M. and Berman, J.W.:  Shedding of PECAM-1 during HIV infection: a potential role for soluble PECAM-1 in the pathogenesis of NeuroAIDS.  J. Leukoc. Biol. 79:444-452, 2006.

Calderon, T.M., Eugenin, E.A., Lopez, L., Kumar, S.S., Hesselgesser, J. Raine, C.S. and Berman, J.W.:  A role for CXCL12 (SDF-1alpha) in the pathogenesis of multiple sclerosis:  regulation of CXCL12 expression in astrocytes by soluble myelin basic protein.  J. Neuroimmunol. 177:27-39, 2006.

Eugenin, E.A., King, J.E., Nath, A., Calderon, T.M., Zukin, R.S., Bennett, M.V. and Berman, J.W.:  HIV-tat induces formation of an LRP-PSD-95-NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes. Proc. Natl. Acad. Sci. U.S.A. 104:3438-3443, 2007.

 

Keywords

Drug Abuse, HIV, Dopamine, Transmigration, SDF-1, CNS, T lymphocyte, Monocyte, Lipid Rafts, Cell Signaling

Material in this section is provided by individual faculty members who are solely responsible for its accuracy and content.

Contact

Albert Einstein College of Medicine
Jack and Pearl Resnick Campus
1300 Morris Park Avenue
Forchheimer Building, Room 727
Bronx, NY 10461

Tel: 718.430.3194
Fax: 718.430.8541
tina.calderon@einstein.yu.edu

 
Pubmed Search
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Additional Information

Summary:

Dopamine modulation of uninfected and HIV infected T lymphocyte and monocyte transmigration into the CNS in response to SDF-1.

Education:

Degree: B.A.
Institute: Harvard University
Department:
Year: 1980
Major: Chemistry

Degree: Ph.D.
Institute: Mount Sinai School of Medicine of CUNY
Department: Biochemistry
Year: 1988
Major: Biomedical Sciences

Degree: Post-Doctoral Fellowship
Institute: Albert Einstein College of Medicine
Department: Pathology
Year: 1988-1991
Major:

Biosketch or CV