Department of Molecular Pharmacology

Explore Our Research

Research in the Department is broad, and includes a training program that encompasses current "state of the art" research that includes investigations on protein phosphorylation, transcriptional regulation  and chromatin modifying proteins, targeting intracellular signals, ion channel regulation, obesity and energy metabolism, signal transduction / cell regulation, autophagy hormone action and biogenesis, molecular basis of therapeutics, membrane transporters, cytoskeleton structure and function, and development of activators and inhibitors. Important methodologies and areas of expertise are: proteomics, RNA interference analysis, protein and phosphoinositide kinases and phosphatases, glycoproteins and lectins, signaling to the nucleus and gene regulation, structural / functional studies of membrane transporters and ion channels, differentiation and development, innate immunity, antitumor drug development and pharmacogenomics.  

Target diseases include: diabetes, cancer, thyroid and cardiac pathogenesis, behavioral disorders, learning and depression, as well as neurodevelopmental and neurodegenerative disorders. Mouse models are frequently used in these efforts, as are human-derived specimens so that our research is at the forefront of translational science. The research program in the department trains Ph.D. and M.D. / Ph.D. students for independent research careers.  Students are key participants in our research endeavors and present their research at national meetings, conferences and symposia.  
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
 

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