Tuesday, October 29, 2013
Aging is a major risk factor for major chronic diseases including cancer, cardiovascular disease and diabetes. Understanding the biological processes that underlie aging could lead to new ways of treating or even preventing chronic disease. The NIH symposium is the first to take an integrated approach to studying diseases associated with aging. Each of its seven panels will focus on a different broad area of research: inflammation, adaption to stress, epigenetics, metabolism, macromolecular damage, proteostasis and adult stem cells and regeneration.
Jeffrey Pessin, Ph.D., director of Einstein's Diabetes Research Center, and Christopher Newgard, Ph.D., of Duke University School of Medicine, will co-chair the panel on metabolism and how making it more efficient could help fight age-related diseases processes. Dr. Pessin holds the Judy R. and Alfred A. Rosenberg Professorial Chair in Diabetes Research and is professor of medicine and of molecular pharmacology at Einstein.
Jan Vijg, Ph.D.Ana Maria Cuervo, M.D., Ph.D., co-director of Einstein's Institute for Aging Research, will co-chair the panel on proteostasis with Richard Morimoto, Ph.D., of Northwestern University. Proteostasis involves preserving cell function by preventing cell proteins from either degrading or accumulating as we age. Dr. Cuervo is professor of developmental and molecular biology, of anatomy and structural biology, and of medicine and holds the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases.
Two other Einstein researchers will make presentations at the summit:
•Dongsheng Cai, M.D., Ph.D.: "Hypothalamic neurodegeneration: a common link between metabolic disease and aging"
•Jan Vijg, Ph.D.: "Does DNA damage or mutations ever rise to high enough frequencies to directly cause functional decline?"
Featuring National Institutes of Health (NIH) director Francis Collins, the "Advances in Geroscience: Impact on Healthspan and Chronic Disease" scientific summit was organized by the trans-NIH Geroscience Interest Group (GSIG) with support from the Alliance for Aging Research and The Gerontological Society of America. Among the largest trans-NIH interest groups, the GSIG focuses on the relationships between aging and age-related disease and disability.
More information and the Summit's agenda are available at http://www.geron.org/meeting2013/GSIG_PreliminaryAgenda.pdf. - See more at: http://einstein.yu.edu/news/releases/950/einstein-researchers-lead-panels-at-nih-aging-and-chronic-disease-symposium-on-geroscience/#sthash.vPD4N3R6.dpuf