Welcome to Molecular Pharmacology. The Department offers a training program that encompasses current “state of the art” research that includes investigations on protein phosphorylation, transcriptional regulation and chromatin modifying proteins, targeting intracellular signals, ion channel regulation, obesity and energy metabolism, signal transduction / cell regulation, autophagy hormone action and biogenesis, molecular basis of therapeutics, membrane transporters, cytoskeleton structure and function, and development of activators and inhibitors. Important methodologies and areas of expertise are: proteomics, RNA interference analysis, protein and phosphoinositide kinases and phosphatases, glycoproteins and lectins, signaling to the nucleus and gene regulation, structural / functional studies of membrane transporters and ion channels, differentiation and development, innate immunity, antitumor drug development and pharmacogenomics. Target diseases include: diabetes, cancer, thyroid and cardiac pathogenesis, behavioral disorders, learning and depression, as well as neurodevelopmental and neurodegenerative disorders. Mouse models are frequently used in these efforts, as are human-derived specimens so that our research is at the forefront of translational science. The research program in the department trains Ph.D. and M.D. / Ph.D. students for independent research careers. Students are key participants in our research endeavors and present their research at national meetings, conferences and symposia.
The Department has 20 faculty members and a cadre of 42 graduate students and postdoctoral fellows who participate in all departmental activities. Numerous scientific collaborations within the Department and with faculty with related interests in other Departments provide students with the opportunity for interactions with multiple faculty members, thus creating a broad-based and dynamic scientific environment. The Department sponsors a seminar series for senior visiting scientists that enables students to interact with distinguished extramural investigators. Journal clubs, work-in-progress research meetings, a weekly Department-wide seminar, a monthly Wednesday afternoon "happy hour" and scientific retreats promote scientific and social interactions among the students, fellows and faculty.
Graduates of the Department of Molecular Pharmacology have earned postdoctoral positions in outstanding laboratories and received prestigious fellowships. Our graduates have permanent positions in academia, biotechnology / pharmaceutical companies and at the National Institutes of Health and the Food and Drug Administration. We are proud of the accomplishments of our graduates and welcome new students to join us as we prepare for a future in science that has limitless potential for progress in basic biomedical knowledge and amelioration of disease.