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Murali Janakiram, Zang Lab
Janakiram, M., Y. M. Abadi, J. A. Sparano, and X. Zang. 2012. T cell coinhibition and immunotherapy in human breast cancer. Discov Med 14:229-236
Revskaya, E., P. Chu, R. C. Howell, A. D. Schweitzer, R. A. Bryan, M. Harris, G. Gerfen, Z. Jiang, T. Jandl, K. Kim, L. M. Ting, R. S. Sellers, E. Dadachova, and A. Casadevall. 2012. Compton scattering by internal shields based on melanin-containing mushrooms provides protection of gastrointestinal tract from ionizing radiation. Cancer Biother Radiopharm 27:570-576
Jandl, T., E. Revskaya, Z. Jiang, M. Harris, O. Dorokhova, D. Tsukrov, A. Casadevall, and E. Dadachova. 2013. Melanoma stem cells in experimental melanoma are killed by radioimmunotherapy. Nucl Med Biol 40:177-181
Jandl, T., E. Revskaya, Z. Jiang, R. A. Bryan, A. Casadevall, and E. Dadachova. 2013. Complement-dependent cytotoxicity of an antibody to melanin in radioimmunotherapy of metastatic melanoma. Immunotherapy 5:357-364
Hofmeyer, K. A., H. Jeon, and X. Zang. 2011. The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion. J Biomed Biotechnol 2011:451694
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Lee Kozakiewicz, Chan Lab
Kozakiewicz, L., J. Phuah, J. Flynn, and J. Chan. 2013. The role of B cells and humoral immunity in Mycobacterium tuberculosis infection. Adv Exp Med Biol 783:225-250
Saidi M'Homa Soudja, Lauvau Lab
Campisi, L., S. M. Soudja, J. Cazareth, D. Bassand, A. Lazzari, F. Brau, E. Narni-Mancinelli, N. Glaichenhaus, F. Geissmann, and G. Lauvau. 2011. Splenic CD8α dendritic cells undergo rapid programming by cytosolic bacteria and inflammation to induce protective CD8 T-cell memory. Eur J Immunol 41:1594-1605
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Madan, R. P., P. M. Mesquita, N. Cheshenko, B. Jing, V. Shende, E. Guzman, T. Heald, M. J. Keller, S. L. Regen, R. J. Shattock, and B. C. Herold. 2007. Molecular umbrellas: a novel class of candidate topical microbicides to prevent human immunodeficiency virus and herpes simplex virus infections. J Virol 81:7636-7646
Fakioglu, E., S. S. Wilson, P. M. Mesquita, E. Hazrati, N. Cheshenko, J. A. Blaho, and B. C. Herold. 2008. Herpes simplex virus downregulates secretory leukocyte protease inhibitor: a novel immune evasion mechanism. J Virol 82:9337-9344
Mesquita, P. M., S. S. Wilson, P. Manlow, L. Fischetti, M. J. Keller, B. C. Herold, and R. J. Shattock. 2008. Candidate microbicide PPCM blocks human immunodeficiency virus type 1 infection in cell and tissue cultures and prevents genital herpes in a murine model. J Virol 82:6576-6584
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Wilson, S. S., N. Cheshenko, E. Fakioglu, P. M. Mesquita, M. J. Keller, and B. C. Herold. 2009. Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a murine model of microbicide safety. Antivir Ther 14:1113-1124
Keller, M. J., P. M. Mesquita, N. M. Torres, S. Cho, G. Shust, R. P. Madan, H. W. Cohen, J. Petrie, T. Ford, L. Soto-Torres, A. T. Profy, and B. C. Herold. 2010. Postcoital bioavailability and antiviral activity of 0.5% PRO 2000 gel: implications for future microbicide clinical trials. PLoS One 5:e8781.
Herold, B. C., P. M. Mesquita, R. P. Madan, and M. J. Keller. 2011. Female genital tract secretions and semen impact the development of microbicides for the prevention of HIV and other sexually transmitted infections. Am J Reprod Immunol 65:325-333
Keller, M. J., R. P. Madan, N. M. Torres, M. J. Fazzari, S. Cho, S. Kalyoussef, G. Shust, P. M. Mesquita, N. Louissaint, J. Chen, H. W. Cohen, E. C. Diament, A. C. Lee, L. Soto-Torres, C. W. Hendrix, and B. C. Herold. 2011. A randomized trial to assess anti-HIV activity in female genital tract secretions and soluble mucosal immunity following application of 1% tenofovir gel. PLoS One 6:e16475
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Mesquita, P. M., R. Rastogi, T. J. Segarra, R. S. Teller, N. M. Torres, A. M. Huber, P. F. Kiser, and B. C. Herold. 2012. Intravaginal ring delivery of tenofovir disoproxil fumarate for prevention of HIV and herpes simplex virus infection. J Antimicrob Chemother 67:1730-1738
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Mukherjee, G., and T. P. Dilorenzo. 2010. The immunotherapeutic potential of dendritic cells in type 1 diabetes. Clin Exp Immunol 161:197-207
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Antal, Z., J. C. Baker, C. Smith, I. Jarchum, J. Babad, G. Mukherjee, Y. Yang, J. Sidney, A. Sette, P. Santamaria, and T. P. DiLorenzo. 2012. Beyond HLA-A*0201: new HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a rich source of CD8+ T cell epitopes. J Immunol 188:5766-5775
Mukherjee, G., A. Geliebter, J. Babad, P. Santamaria, D. V. Serreze, G. J. Freeman, K. V. Tarbell, A. Sharpe, and T. P. DiLorenzo. DEC-205–mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8 T cells independently of PD-1 and PD-L1. Int Immunol in press
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McClelland, E. E., A. M. Nicola, R. Prados-Rosales, and A. Casadevall. 2010. Ab binding alters gene expression in Cryptococcus neoformans and directly modulates fungal metabolism. J Clin Invest 120:1355-1361
Prados-Rosales, R., A. Baena, L. R. Martinez, J. Luque-Garcia, R. Kalscheuer, U. Veeraraghavan, C. Camara, J. D. Nosanchuk, G. S. Besra, B. Chen, J. Jimenez, A. Glatman-Freedman, W. R. Jacobs, Jr., S. A. Porcelli, and A. Casadevall. 2011. Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice. J Clin Invest 121:1471-1483
Siev, M., X. Yu, R. Prados-Rosales, F. T. Martiniuk, A. Casadevall, and J. M. Achkar. 2011. Correlation between serum and plasma antibody titers to mycobacterial antigens. Clin Vaccine Immunol 18:173-175
Yu, X., R. Prados-Rosales, E. R. Jenny-Avital, K. Sosa, A. Casadevall, and J. M. Achkar. 2012. Comparative evaluation of profiles of antibodies to mycobacterial capsular polysaccharides in tuberculosis patients and controls stratified by HIV status. Clin Vaccine Immunol 19:198-208
Chatterjee, S., R. Prados-Rosales, S. Frases, B. Itin, A. Casadevall, and R. E. Stark. 2012. Using solid-state NMR to monitor the molecular consequences of Cryptococcus neoformans melanization with different catecholamine precursors. Biochemistry 51:6080-6088
Ziegenbalg, A., R. Prados-Rosales, E. R. Jenny-Avital, R. S. Kim, A. Casadevall, and J. M. Achkar. 2013. Immunogenicity of mycobacterial vesicles in humans: Identification of a new tuberculosis antibody biomarker. Tuberculosis (Edinb) 93:448-455
Kania, G., S. Siegert, S. Behnke, R. Prados-Rosales, A. Casadevall, T. F. Luscher, S. A. Luther, M. Kopf, U. Eriksson, and P. Blyszczuk. 2013. Innate signaling promotes formation of regulatory nitric oxide-producing dendritic cells limiting T-cell expansion in experimental autoimmune myocarditis. Circulation 127:2285-2294
Dadachova, E., R. A. Bryan, C. Apostolidis, A. Morgenstern, T. Zhang, T. Moadel, M. Torres, X. Huang, E. Revskaya, and A. Casadevall. 2006. Interaction of radiolabeled antibodies with fungal cells and components of the immune system in vitro and during radioimmunotherapy for experimental fungal infection. J Infect Dis 193:1427-1436
Dadachova, E., T. Moadel, A. D. Schweitzer, R. A. Bryan, T. Zhang, L. Mints, E. Revskaya, X. Huang, G. Ortiz, J. S. Nosanchuk, J. D. Nosanchuk, and A. Casadevall. 2006. Radiolabeled melanin-binding peptides are safe and effective in treatment of human pigmented melanoma in a mouse model of disease. Cancer Biother Radiopharm 21:117-129
Howell, R. C., E. Revskaya, V. Pazo, J. D. Nosanchuk, A. Casadevall, and E. Dadachova. 2007. Phage display library derived peptides that bind to human tumor melanin as potential vehicles for targeted radionuclide therapy of metastatic melanoma. Bioconjug Chem 18:1739-1748
Schweitzer, A. D., V. Rakesh, E. Revskaya, A. Datta, A. Casadevall, and E. Dadachova. 2007. Computational model predicts effective delivery of 188-Re-labeled melanin-binding antibody to metastatic melanoma tumors with wide range of melanin concentrations. Melanoma Res 17:291-303
Wang, X. G., E. Revskaya, R. A. Bryan, H. D. Strickler, R. D. Burk, A. Casadevall, and E. Dadachova. 2007. Treating cancer as an infectious disease--viral antigens as novel targets for treatment and potential prevention of tumors of viral etiology. PLoS One 2:e1114
Dadachova, E., E. Revskaya, M. A. Sesay, H. Damania, R. Boucher, R. S. Sellers, R. C. Howell, L. Burns, G. B. Thornton, A. Natarajan, G. R. Mirick, S. J. DeNardo, G. L. DeNardo, and A. Casadevall. 2008. Pre-clinical evaluation and efficacy studies of a melanin-binding IgM antibody labeled with 188Re against experimental human metastatic melanoma in nude mice. Cancer Biol Ther 7:1116-1127
Dadachova, E., J. Rivera, E. Revskaya, A. Nakouzi, S. M. Cahill, M. Blumenstein, H. Xiao, D. Rykunov, and A. Casadevall. 2008. In vitro evaluation, biodistribution and scintigraphic imaging in mice of radiolabeled anthrax toxins. Nucl Med Biol 35:755-761
Revskaya, E., A. M. Jongco, R. S. Sellers, R. C. Howell, W. Koba, A. J. Guimaraes, J. D. Nosanchuk, A. Casadevall, and E. Dadachova. 2009. Radioimmunotherapy of experimental human metastatic melanoma with melanin-binding antibodies and in combination with dacarbazine. Clin Cancer Res 15:2373-2379
Rivera, J., A. Nakouzi, N. Abboud, E. Revskaya, D. Goldman, R. J. Collier, E. Dadachova, and A. Casadevall. 2006. A monoclonal antibody to Bacillus anthracis protective antigen defines a neutralizing epitope in domain 1. Infect Immun 74:4149-4156.
Schweitzer, A. D., E. Revskaya, P. Chu, V. Pazo, M. Friedman, J. D. Nosanchuk, S. Cahill, S. Frases, A. Casadevall, and E. Dadachova. 2010. Melanin-covered nanoparticles for protection of bone marrow during radiation therapy of cancer. Int J Radiat Oncol Biol Phys 78:1494-1502
Ballard, B., Z. Jiang, C. E. Soll, E. Revskaya, C. S. Cutler, E. Dadachova, and L. C. Francesconi. 2011. In vitro and in vivo evaluation of melanin-binding decapeptide 4B4 radiolabeled with 177Lu, 166Ho, and 153Sm radiolanthanides for the purpose of targeted radionuclide therapy of melanoma. Cancer Biother Radiopharm 26:547-556
Dadachova, E., S. G. Kitchen, G. Bristol, G. C. Baldwin, E. Revskaya, C. Empig, G. B. Thornton, M. K. Gorny, S. Zolla-Pazner, and A. Casadevall. 2012. Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication. PLoS One 7:e31866
Revskaya, E., P. Chu, R. C. Howell, A. D. Schweitzer, R. A. Bryan, M. Harris, G. Gerfen, Z. Jiang, T. Jandl, K. Kim, L. M. Ting, R. S. Sellers, E. Dadachova, and A. Casadevall. 2012. Compton scattering by internal shields based on melanin-containing mushrooms provides protection of gastrointestinal tract from ionizing radiation. Cancer Biother Radiopharm 27:570-576
Jandl, T., E. Revskaya, Z. Jiang, M. Harris, O. Dorokhova, D. Tsukrov, A. Casadevall, and E. Dadachova. 2013. Melanoma stem cells in experimental melanoma are killed by radioimmunotherapy. Nucl Med Biol 40:177-181
Klein, M., M. Lotem, T. Peretz, S. T. Zwas, S. Mizrachi, Y. Liberman, R. Chisin, J. Schachter, I. G. Ron, G. Iosilevsky, J. A. Kennedy, E. Revskaya, A. W. de Kater, E. Banaga, V. Klutzaritz, N. Friedmann, E. Galun, G. L. Denardo, S. J. Denardo, A. Casadevall, E. Dadachova, and G. B. Thornton. 2013. Safety and efficacy of 188-rhenium-labeled antibody to melanin in patients with metastatic melanoma. J Skin Cancer 2013:828329
Jandl, T., E. Revskaya, Z. Jiang, R. A. Bryan, A. Casadevall, and E. Dadachova. 2013. Complement-dependent cytotoxicity of an antibody to melanin in radioimmunotherapy of metastatic melanoma. Immunotherapy 5:357-364
Samanta, D., G. Mukherjee, U. A. Ramagopal, R. J. Chaparro, S. G. Nathenson, T. P. DiLorenzo, and S. C. Almo. 2011. Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells. Proc Natl Acad Sci USA 108:13682-13687
Samanta, D., U. A. Ramagopal, R. Rubinstein, V. Vigdorovich, S. G. Nathenson, and S. C. Almo. 2012. Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion. Proc Natl Acad Sci U S A 109:14836-14840
Lisa Scandiuzzi, Zang Lab
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