Department of Microbiology & Immunology

Fellow publications

 

Fabrizio Biundo, D'Adamio Lab 

Matrone, C., S. Luvisetto, L. R. La Rosa, R. Tamayev, A. Pignataro, N. Canu, L. Yang, A. P. Barbagallo, F. Biundo, F. Lombino, H. Zheng, M. Ammassari-Teule, and L. D'Adamio. 2012. Tyr682 in the Abeta-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance. Aging Cell 11:1084-1093

Lombino, F., F. Biundo, R. Tamayev, O. Arancio, and L. D'Adamio. 2013. An intracellular threonine of amyloid-beta precursor protein mediates synaptic plasticity deficits and memory loss. PLoS One 8:e57120

 

 

 

Leandro Carreno, Porcelli Lab 

Wen, X., P. Rao, L. J. Carreno, S. Kim, A. Lawrenczyk, S. A. Porcelli, P. Cresswell, and W. Yuan. 2013. Human CD1d knock-in mouse model demonstrates potent antitumor potential of human CD1d-restricted invariant natural killer T cells. Proc Natl Acad Sci U S A 110:2963-2968

Arora, P., A. Baena, K. O. Yu, N. K. Saini, S. S. Kharkwal, M. F. Goldberg, S. Kunnath-Velayudhan, L. J. Carreno, M. M. Venkataswamy, J. Kim, E. Lazar-Molnar, G. Lauvau, Y. T. Chang, Z. Liu, R. Bittman, A. Al-Shamkhani, L. R. Cox, P. J. Jervis, N. Veerapen, G. S. Besra, and S. A. Porcelli. 2014. A single subset of dendritic cells controls the cytokine bias of natural killer T cell responses to diverse glycolipid antigens. Immunity 40:105-116

Carreno, L. J., S. S. Kharkwal, and S. A. Porcelli. 2014. Optimizing NKT cell ligands as vaccine adjuvants. Immunotherapy 6:309-320

Venkataswamy, M. M., T. W. Ng, S. S. Kharkwal, L. J. Carreno, A. J. Johnson, S. Kunnath-Velayudhan, Z. Liu, R. Bittman, P. J. Jervis, L. R. Cox, G. S. Besra, X. Wen, W. Yuan, M. Tsuji, X. Li, D. D. Ho, J. Chan, S. Lee, R. Frothingham, B. F. Haynes, M. W. Panas, G. O. Gillard, J. D. Sixsmith, B. Korioth-Schmitz, J. E. Schmitz, M. H. Larsen, W. R. Jacobs, Jr., and S. A. Porcelli. 2014. Improving Mycobacterium bovis Bacillus Calmette-Guerin as a vaccine delivery vector for viral antigens by incorporation of glycolipid activators of NKT cells. PLoS One 9:e108383

 

 

 

Laurent Chorro, Lauvau Lab 

Lauvau, G., L. Chorro, E. Spaulding, and S. M. Soudja. 2014. Inflammatory monocyte effector mechanisms. Cell Immunol (in press)

 

 

 

Ian Cook, Leyh Lab 

Cook, I. T., T. S. Leyh, S. A. Kadlubar, and C. N. Falany. 2010. Structural rearrangement of SULT2A1: effects on dehydroepiandrosterone and raloxifene sulfation. Horm Mol Biol Clin Investig 1:81-87

Cook, I. T., T. S. Leyh, S. A. Kadlubar, and C. N. Falany. 2010. Lack of substrate inhibition in a monomeric form of human cytosolic SULT2A1. Horm Mol Biol Clin Investig 3:357-366

Rohn, K. J., I. T. Cook, T. S. Leyh, S. A. Kadlubar, and C. N. Falany. 2012. Potent inhibition of human sulfotransferase 1A1 by 17alpha-ethinylestradiol: role of 3'-phosphoadenosine 5'-phosphosulfate binding and structural rearrangements in regulating inhibition and activity. Drug Metab Dispos 40:1588-1595

Cook, I., T. Wang, C. N. Falany, and T. S. Leyh. 2012. A nucleotide-gated molecular pore selects sulfotransferase substrates. Biochemistry 51:5674-5683

Cook, I., T. Wang, S. C. Almo, J. Kim, C. N. Falany, and T. S. Leyh. 2013. The gate that governs sulfotransferase selectivity. Biochemistry 52:415-424

Cook, I., T. Wang, S. C. Almo, J. Kim, C. N. Falany, and T. S. Leyh. 2013. Testing the sulfotransferase molecular pore hypothesis. J Biol Chem 288:8619-8626

Leyh, T. S., I. Cook, and T. Wang. 2013. Structure, dynamics and selectivity in the sulfotransferase family. Drug Metab Rev 45:423-430

Cook, I., T. Wang, C. N. Falany, and T. S. Leyh. 2013. High accuracy in silico sulfotransferase models. J Biol Chem 288:34494-34501

Wang, T., I. Cook, C. N. Falany, and T. S. Leyh. 2014. Paradigms of sulfotransferase catalysis: the mechanism of SULT2A1. J Biol Chem 289:26474-26480

 

 

 

Dolores Del Prete, D'Adamio Lab 

Del Prete, D., F. Lombino, X. Liu, and L. D'Adamio. 2014. APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functions. PLoS One 9:e108576

 
 
 

Susan Irvin, Herold Lab 

Murphy, K., S. C. Irvin, and B. C. Herold. 2014. Research gaps in defining the biological link between HIV risk and hormonal contraception. Am J Reprod Immunol 72:228-235

 
 
 

Arthee Jahangir, Gravekamp Lab 

Quispe-Tintaya, W., D. Chandra, A. Jahangir, M. Harris, A. Casadevall, E. Dadachova, and C. Gravekamp. 2013. Nontoxic radioactive Listeriaat is a highly effective therapy against metastatic pancreatic cancer. Proc Natl Acad Sci USA 110:8668-8673

Chandra, D., A. Jahangir, W. Quispe-Tintaya, M. H. Einstein, and C. Gravekamp. 2013. Myeloid-derived suppressor cells have a central role in attenuated Listeria monocytogenes-based immunotherapy against metastatic breast cancer in young and old mice. Br J Cancer 108:2281-2290

Singh, M., I. Ramos, D. Asafu-Adjei, W. Quispe-Tintaya, D. Chandra, A. Jahangir, X. Zang, B. B. Aggarwal, and C. Gravekamp. 2013. Curcumin improves the therapeutic efficacy of Listeriaat-Mage-b vaccine in correlation with improved T-cell responses in blood of a triple-negative breast cancer model 4T1. Cancer Med 2:571-582

Gravekamp, C., and A. Jahangir. 2014. Is cancer vaccination feasible at older age? Exp Gerontol 54:138-144

Chandra, D., W. Quispe-Tintaya, A. Jahangir, D. Asafu-Adjei, I. Ramos, H. O. Sintim, J. Zhou, Y. Hayakawa, D. K. Karaolis, and C. Gravekamp. 2014. STING ligand c-di-GMP improves cancer vaccination against metastatic breast cancer. Cancer Immunol Res 2:901-910

 
 
 

Murali Janakiram, Zang Lab 

Janakiram, M., Y. M. Abadi, J. A. Sparano, and X. Zang. 2012. T cell coinhibition and immunotherapy in human breast cancer. Discov Med 14:229-236

 
 
 

Thomas Jandl, Dadachova Lab 

Revskaya, E., P. Chu, R. C. Howell, A. D. Schweitzer, R. A. Bryan, M. Harris, G. Gerfen, Z. Jiang, T. Jandl, K. Kim, L. M. Ting, R. S. Sellers, E. Dadachova, and A. Casadevall. 2012. Compton scattering by internal shields based on melanin-containing mushrooms provides protection of gastrointestinal tract from ionizing radiation. Cancer Biother Radiopharm 27:570-576

Jandl, T., E. Revskaya, Z. Jiang, M. Harris, O. Dorokhova, D. Tsukrov, A. Casadevall, and E. Dadachova. 2013. Melanoma stem cells in experimental melanoma are killed by radioimmunotherapy. Nucl Med Biol 40:177-181

Jandl, T., E. Revskaya, Z. Jiang, R. A. Bryan, A. Casadevall, and E. Dadachova. 2013. Complement-dependent cytotoxicity of an antibody to melanin in radioimmunotherapy of metastatic melanoma. Immunotherapy 5:357-364

Bryan, R. A., Z. Jiang, T. Jandl, J. Strauss, W. Koba, C. Onyedika, A. Morgenstern, F. Bruchertseifer, A. L. Epstein, and E. Dadachova. 2014. Treatment of experimental pancreatic cancer with 213-Bismuth-labeled chimeric antibody to single-strand DNA. Expert Rev Anticancer Ther 14:1243-1249

Wang, X. G., T. Jandl, E. Dadachova, and E. Revskaya. 2014. Effect of naive and radiolabeled rhTRAIL on the cervical cancer xenografts in mice. Ther Deliv 5:139-147

 
 
 

Hyungjun Jeon, Zang Lab 

Hofmeyer, K. A., H. Jeon, and X. Zang. 2011. The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion. J Biomed Biotechnol 2011:451694

Abadi, Y. M., H. Jeon, K. C. Ohaegbulam, L. Scandiuzzi, K. Ghosh, K. A. Hofmeyer, J. S. Lee, A. Ray, C. Gravekamp, and X. Zang. 2013. Host B7x promotes pulmonary metastasis of breast cancer. J Immunol 190:3806-3814

Zhao, R., J. M. Chinai, S. Buhl, L. Scandiuzzi, A. Ray, H. Jeon, K. C. Ohaegbulam, K. Ghosh, A. Zhao, M. D. Scharff, and X. Zang. 2013. HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function. Proc Natl Acad Sci U S A 110:9879-9884

Jeon, H., K. C. Ohaegbulam, Y. M. Abadi, and X. Zang. 2013. B7x and myeloid-derived suppressor cells in the tumor microenvironment: A tale of two cities. Oncoimmunology 2:e24744

Scandiuzzi, L., K. Ghosh, K. A. Hofmeyer, Y. M. Abadi, E. Lazar-Molnar, E. Y. Lin, Q. Liu, H. Jeon, S. C. Almo, L. Chen, S. G. Nathenson, and X. Zang. 2014. Tissue-expressed B7-H1 critically controls intestinal inflammation. Cell Rep 6:625-632

 
 
 

Alison Johnson, Porcelli Lab 

Venkataswamy, M. M., T. W. Ng, S. S. Kharkwal, L. J. Carreno, A. J. Johnson, S. Kunnath-Velayudhan, Z. Liu, R. Bittman, P. J. Jervis, L. R. Cox, G. S. Besra, X. Wen, W. Yuan, M. Tsuji, X. Li, D. D. Ho, J. Chan, S. Lee, R. Frothingham, B. F. Haynes, M. W. Panas, G. O. Gillard, J. D. Sixsmith, B. Korioth-Schmitz, J. E. Schmitz, M. H. Larsen, W. R. Jacobs, Jr., and S. A. Porcelli. 2014. Improving Mycobacterium bovis Bacillus Calmette-Guerin as a vaccine delivery vector for viral antigens by incorporation of glycolipid activators of NKT cells. PLoS One 9:e108383

 

 

 

Shajo Kunnath Velayudhan, Porcelli Lab 

Kunnath-Velayudhan, S., and S. A. Porcelli. 2013. Recent advances in defining the immunoproteome of Mycobacterium tuberculosis. Front Immunol 4:335

Arora, P., A. Baena, K. O. Yu, N. K. Saini, S. S. Kharkwal, M. F. Goldberg, S. Kunnath-Velayudhan, L. J. Carreno, M. M. Venkataswamy, J. Kim, E. Lazar-Molnar, G. Lauvau, Y. T. Chang, Z. Liu, R. Bittman, A. Al-Shamkhani, L. R. Cox, P. J. Jervis, N. Veerapen, G. S. Besra, and S. A. Porcelli. 2014. A single subset of dendritic cells controls the cytokine bias of natural killer T cell responses to diverse glycolipid antigens. Immunity 40:105-116

Venkataswamy, M. M., T. W. Ng, S. S. Kharkwal, L. J. Carreno, A. J. Johnson, S. Kunnath-Velayudhan, Z. Liu, R. Bittman, P. J. Jervis, L. R. Cox, G. S. Besra, X. Wen, W. Yuan, M. Tsuji, X. Li, D. D. Ho, J. Chan, S. Lee, R. Frothingham, B. F. Haynes, M. W. Panas, G. O. Gillard, J. D. Sixsmith, B. Korioth-Schmitz, J. E. Schmitz, M. H. Larsen, W. R. Jacobs, Jr., and S. A. Porcelli. 2014. Improving Mycobacterium bovis Bacillus Calmette-Guerin as a vaccine delivery vector for viral antigens by incorporation of glycolipid activators of NKT cells. PLoS One 9:e108383

 

 

 

Pedro Mesquita, Herold Lab 

Madan, R. P., P. M. Mesquita, N. Cheshenko, B. Jing, V. Shende, E. Guzman, T. Heald, M. J. Keller, S. L. Regen, R. J. Shattock, and B. C. Herold. 2007. Molecular umbrellas: a novel class of candidate topical microbicides to prevent human immunodeficiency virus and herpes simplex virus infections. J Virol 81:7636-7646

Fakioglu, E., S. S. Wilson, P. M. Mesquita, E. Hazrati, N. Cheshenko, J. A. Blaho, and B. C. Herold. 2008. Herpes simplex virus downregulates secretory leukocyte protease inhibitor: a novel immune evasion mechanism. J Virol 82:9337-9344

Mesquita, P. M., S. S. Wilson, P. Manlow, L. Fischetti, M. J. Keller, B. C. Herold, and R. J. Shattock. 2008. Candidate microbicide PPCM blocks human immunodeficiency virus type 1 infection in cell and tissue cultures and prevents genital herpes in a murine model. J Virol 82:6576-6584

Mesquita, P. M., N. Cheshenko, S. S. Wilson, M. Mhatre, E. Guzman, E. Fakioglu, M. J. Keller, and B. C. Herold. 2009. Disruption of tight junctions by cellulose sulfate facilitates HIV infection: model of microbicide safety. J Infect Dis 200:599-608

Wilson, S. S., N. Cheshenko, E. Fakioglu, P. M. Mesquita, M. J. Keller, and B. C. Herold. 2009. Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a murine model of microbicide safety. Antivir Ther 14:1113-1124

Keller, M. J., P. M. Mesquita, N. M. Torres, S. Cho, G. Shust, R. P. Madan, H. W. Cohen, J. Petrie, T. Ford, L. Soto-Torres, A. T. Profy, and B. C. Herold. 2010. Postcoital bioavailability and antiviral activity of 0.5% PRO 2000 gel: implications for future microbicide clinical trials. PLoS One 5:e8781.

Herold, B. C., P. M. Mesquita, R. P. Madan, and M. J. Keller. 2011. Female genital tract secretions and semen impact the development of microbicides for the prevention of HIV and other sexually transmitted infections. Am J Reprod Immunol 65:325-333

Keller, M. J., R. P. Madan, N. M. Torres, M. J. Fazzari, S. Cho, S. Kalyoussef, G. Shust, P. M. Mesquita, N. Louissaint, J. Chen, H. W. Cohen, E. C. Diament, A. C. Lee, L. Soto-Torres, C. W. Hendrix, and B. C. Herold. 2011. A randomized trial to assess anti-HIV activity in female genital tract secretions and soluble mucosal immunity following application of 1% tenofovir gel. PLoS One 6:e16475

Segarra, T. J., E. Fakioglu, N. Cheshenko, S. S. Wilson, P. M. Mesquita, G. F. Doncel, and B. C. Herold. 2011. Bridging the gap between preclinical and clinical microbicide trials: blind evaluation of candidate gels in murine models of efficacy and safety. PLoS One 6:e27675

Mesquita, P. M., R. Rastogi, T. J. Segarra, R. S. Teller, N. M. Torres, A. M. Huber, P. F. Kiser, and B. C. Herold. 2012. Intravaginal ring delivery of tenofovir disoproxil fumarate for prevention of HIV and herpes simplex virus infection. J Antimicrob Chemother 67:1730-1738

Kiser, P. F., P. M. Mesquita, and B. C. Herold. 2012. A perspective on progress and gaps in HIV prevention science. AIDS Res Hum Retroviruses 28:1373-1378

Nixon, B., M. Stefanidou, P. M. Mesquita, E. Fakioglu, T. Segarra, L. Rohan, W. Halford, K. E. Palmer, and B. C. Herold. 2013. Griffithsin protects mice from genital herpes by preventing cell-to-cell spread. J Virol 87:6257-6269

Rastogi, R., R. S. Teller, P. M. Mesquita, B. C. Herold, and P. F. Kiser. 2013. Osmotic pump tablets for delivery of antiretrovirals to the vaginal mucosa. Antiviral Res 100:255-258

Smith, J. M., R. Rastogi, R. S. Teller, P. Srinivasan, P. M. Mesquita, U. Nagaraja, J. M. McNicholl, R. M. Hendry, C. T. Dinh, A. Martin, B. C. Herold, and P. F. Kiser. 2013. Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges. Proc Natl Acad Sci U S A 110:16145-16150

Mesquita, P. M., P. Srinivasan, T. J. Johnson, R. Rastogi, T. Evans-Strickfaden, M. S. Kay, K. W. Buckheit, R. W. Buckheit, Jr., J. M. Smith, P. F. Kiser, and B. C. Herold. 2013. Novel preclinical models of topical PrEP pharmacodynamics provide rationale for combination of drugs with complementary properties. Retrovirology 10:113

Herold, B. C., C. S. Dezzutti, B. A. Richardson, J. Marrazzo, P. M. Mesquita, C. Carpenter, A. Huber, N. Louissaint, M. A. Marzinke, S. L. Hillier, and C. W. Hendrix. 2014. Antiviral activity of genital tract secretions after oral or topical tenofovir pre-exposure prophylaxis for HIV-1. J Acquir Immune Defic Syndr 66:65-73

Jackson, A. G., L. J. Else, P. M. Mesquita, D. Egan, D. J. Back, Z. Karolia, L. Ringner-Nackter, C. J. Higgs, B. C. Herold, B. G. Gazzard, and M. Boffito. 2014. A compartmental pharmacokinetic evaluation of long-acting rilpivirine in HIV-negative volunteers for pre-exposure prophylaxis. Clin Pharmacol Ther 96:314-323

 
 
 

Ekaterina Revskaya, Dadachova Lab 

Dadachova, E., R. A. Bryan, C. Apostolidis, A. Morgenstern, T. Zhang, T. Moadel, M. Torres, X. Huang, E. Revskaya, and A. Casadevall. 2006. Interaction of radiolabeled antibodies with fungal cells and components of the immune system in vitro and during radioimmunotherapy for experimental fungal infection. J Infect Dis 193:1427-1436

Dadachova, E., T. Moadel, A. D. Schweitzer, R. A. Bryan, T. Zhang, L. Mints, E. Revskaya, X. Huang, G. Ortiz, J. S. Nosanchuk, J. D. Nosanchuk, and A. Casadevall. 2006. Radiolabeled melanin-binding peptides are safe and effective in treatment of human pigmented melanoma in a mouse model of disease. Cancer Biother Radiopharm 21:117-129

Howell, R. C., E. Revskaya, V. Pazo, J. D. Nosanchuk, A. Casadevall, and E. Dadachova. 2007. Phage display library derived peptides that bind to human tumor melanin as potential vehicles for targeted radionuclide therapy of metastatic melanoma. Bioconjug Chem 18:1739-1748

Schweitzer, A. D., V. Rakesh, E. Revskaya, A. Datta, A. Casadevall, and E. Dadachova. 2007. Computational model predicts effective delivery of 188-Re-labeled melanin-binding antibody to metastatic melanoma tumors with wide range of melanin concentrations. Melanoma Res 17:291-303

Wang, X. G., E. Revskaya, R. A. Bryan, H. D. Strickler, R. D. Burk, A. Casadevall, and E. Dadachova. 2007. Treating cancer as an infectious disease--viral antigens as novel targets for treatment and potential prevention of tumors of viral etiology. PLoS One 2:e1114

Dadachova, E., E. Revskaya, M. A. Sesay, H. Damania, R. Boucher, R. S. Sellers, R. C. Howell, L. Burns, G. B. Thornton, A. Natarajan, G. R. Mirick, S. J. DeNardo, G. L. DeNardo, and A. Casadevall. 2008. Pre-clinical evaluation and efficacy studies of a melanin-binding IgM antibody labeled with 188Re against experimental human metastatic melanoma in nude mice. Cancer Biol Ther 7:1116-1127

Dadachova, E., J. Rivera, E. Revskaya, A. Nakouzi, S. M. Cahill, M. Blumenstein, H. Xiao, D. Rykunov, and A. Casadevall. 2008. In vitro evaluation, biodistribution and scintigraphic imaging in mice of radiolabeled anthrax toxins. Nucl Med Biol 35:755-761

Revskaya, E., A. M. Jongco, R. S. Sellers, R. C. Howell, W. Koba, A. J. Guimaraes, J. D. Nosanchuk, A. Casadevall, and E. Dadachova. 2009. Radioimmunotherapy of experimental human metastatic melanoma with melanin-binding antibodies and in combination with dacarbazine. Clin Cancer Res 15:2373-2379

Rivera, J., A. Nakouzi, N. Abboud, E. Revskaya, D. Goldman, R. J. Collier, E. Dadachova, and A. Casadevall. 2006. A monoclonal antibody to Bacillus anthracis protective antigen defines a neutralizing epitope in domain 1. Infect Immun 74:4149-4156.

Schweitzer, A. D., E. Revskaya, P. Chu, V. Pazo, M. Friedman, J. D. Nosanchuk, S. Cahill, S. Frases, A. Casadevall, and E. Dadachova. 2010. Melanin-covered nanoparticles for protection of bone marrow during radiation therapy of cancer. Int J Radiat Oncol Biol Phys 78:1494-1502

Ballard, B., Z. Jiang, C. E. Soll, E. Revskaya, C. S. Cutler, E. Dadachova, and L. C. Francesconi. 2011. In vitro and in vivo evaluation of melanin-binding decapeptide 4B4 radiolabeled with 177Lu, 166Ho, and 153Sm radiolanthanides for the purpose of targeted radionuclide therapy of melanoma. Cancer Biother Radiopharm 26:547-556

Dadachova, E., S. G. Kitchen, G. Bristol, G. C. Baldwin, E. Revskaya, C. Empig, G. B. Thornton, M. K. Gorny, S. Zolla-Pazner, and A. Casadevall. 2012. Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication. PLoS One 7:e31866

Revskaya, E., P. Chu, R. C. Howell, A. D. Schweitzer, R. A. Bryan, M. Harris, G. Gerfen, Z. Jiang, T. Jandl, K. Kim, L. M. Ting, R. S. Sellers, E. Dadachova, and A. Casadevall. 2012. Compton scattering by internal shields based on melanin-containing mushrooms provides protection of gastrointestinal tract from ionizing radiation. Cancer Biother Radiopharm 27:570-576

Jandl, T., E. Revskaya, Z. Jiang, M. Harris, O. Dorokhova, D. Tsukrov, A. Casadevall, and E. Dadachova. 2013. Melanoma stem cells in experimental melanoma are killed by radioimmunotherapy. Nucl Med Biol 40:177-181

Klein, M., M. Lotem, T. Peretz, S. T. Zwas, S. Mizrachi, Y. Liberman, R. Chisin, J. Schachter, I. G. Ron, G. Iosilevsky, J. A. Kennedy, E. Revskaya, A. W. de Kater, E. Banaga, V. Klutzaritz, N. Friedmann, E. Galun, G. L. Denardo, S. J. Denardo, A. Casadevall, E. Dadachova, and G. B. Thornton. 2013. Safety and efficacy of 188-rhenium-labeled antibody to melanin in patients with metastatic melanoma. J Skin Cancer 2013:828329

Jandl, T., E. Revskaya, Z. Jiang, R. A. Bryan, A. Casadevall, and E. Dadachova. 2013. Complement-dependent cytotoxicity of an antibody to melanin in radioimmunotherapy of metastatic melanoma. Immunotherapy 5:357-364

Thompson, S., B. Ballard, Z. Jiang, E. Revskaya, N. Sisay, W. H. Miller, C. S. Cutler, E. Dadachova, and L. C. Francesconi. 2014. 166Ho and 90Y labeled 6D2 monoclonal antibody for targeted radiotherapy of melanoma: comparison with 188Re radiolabel. Nucl Med Biol 41:276-281

Wang, X. G., T. Jandl, E. Dadachova, and E. Revskaya. 2014. Effect of naive and radiolabeled rhTRAIL on the cervical cancer xenografts in mice. Ther Deliv 5:139-147

 
 
 

Neeraj Saini, Porcelli Lab 

Arora, P., A. Baena, K. O. Yu, N. K. Saini, S. S. Kharkwal, M. F. Goldberg, S. Kunnath-Velayudhan, L. J. Carreno, M. M. Venkataswamy, J. Kim, E. Lazar-Molnar, G. Lauvau, Y. T. Chang, Z. Liu, R. Bittman, A. Al-Shamkhani, L. R. Cox, P. J. Jervis, N. Veerapen, G. S. Besra, and S. A. Porcelli. 2014. A single subset of dendritic cells controls the cytokine bias of natural killer T cell responses to diverse glycolipid antigens. Immunity 40:105-116

 
 
 

Bianca Schulte, Diaz-Griffero Lab 

Fricke, T., T. E. White, B. Schulte, D. A. de Souza Aranha Vieira, A. Dharan, E. M. Campbell, A. Brandariz-Nunez, and F. Diaz-Griffero. 2014. MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1. Retrovirology 11:68

 

 

 

Shalu Sharma, Porcelli Lab 

Arora, P., A. Baena, K. O. Yu, N. K. Saini, S. S. Kharkwal, M. F. Goldberg, S. Kunnath-Velayudhan, L. J. Carreno, M. M. Venkataswamy, J. Kim, E. Lazar-Molnar, G. Lauvau, Y. T. Chang, Z. Liu, R. Bittman, A. Al-Shamkhani, L. R. Cox, P. J. Jervis, N. Veerapen, G. S. Besra, and S. A. Porcelli. 2014. A single subset of dendritic cells controls the cytokine bias of natural killer T cell responses to diverse glycolipid antigens. Immunity 40:105-116

Carreno, L. J., S. S. Kharkwal, and S. A. Porcelli. 2014. Optimizing NKT cell ligands as vaccine adjuvants. Immunotherapy 6:309-320

Venkataswamy, M. M., T. W. Ng, S. S. Kharkwal, L. J. Carreno, A. J. Johnson, S. Kunnath-Velayudhan, Z. Liu, R. Bittman, P. J. Jervis, L. R. Cox, G. S. Besra, X. Wen, W. Yuan, M. Tsuji, X. Li, D. D. Ho, J. Chan, S. Lee, R. Frothingham, B. F. Haynes, M. W. Panas, G. O. Gillard, J. D. Sixsmith, B. Korioth-Schmitz, J. E. Schmitz, M. H. Larsen, W. R. Jacobs, Jr., and S. A. Porcelli. 2014. Improving Mycobacterium bovis Bacillus Calmette-Guerin as a vaccine delivery vector for viral antigens by incorporation of glycolipid activators of NKT cells. PLoS One 9:e108383

 

 

 

Martha Stefanidou, Herold Lab 

Patel, M., M. Stefanidou, C. B. Long, M. J. Fazzari, L. Tesfa, M. Del Rio, J. Lamour, R. Ricafort, R. P. Madan, and B. C. Herold. 2011. Dynamics of cell-mediated immune responses to cytomegalovirus in pediatric transplantation recipients. Pediatr Transplant 16:18-28

Stefanidou, M., I. Ramos, V. Mas Casullo, J. B. Trepanier, S. Rosenbaum, A. Fernandez-Sesma, and B. C. Herold. 2013. Herpes simplex virus 2 (HSV-2) prevents dendritic cell maturation, induces apoptosis, and triggers release of proinflammatory cytokines: potential links to HSV-HIV synergy. J Virol 87:1443-1453

Nixon, B., M. Stefanidou, P. M. Mesquita, E. Fakioglu, T. Segarra, L. Rohan, W. Halford, K. E. Palmer, and B. C. Herold. 2013. Griffithsin protects mice from genital herpes by preventing cell-to-cell spread. J Virol 87:6257-6269

Cheshenko, N., J. B. Trepanier, M. Stefanidou, N. Buckley, P. Gonzalez, W. Jacobs, and B. C. Herold. 2013. HSV activates Akt to trigger calcium release and promote viral entry: novel candidate target for treatment and suppression. FASEB J 27:2584-2599

Nixon, B., E. Fakioglu, M. Stefanidou, Y. Wang, M. Dutta, H. Goldstein, and B. C. Herold. 2014. Genital herpes simplex virus type 2 infection in humanized HIV-transgenic mice triggers HIV shedding and is associated with greater neurological disease. J Infect Dis 209:510-522

 
 
 

Sabriya Stukes, Casadevall Lab 

Liu, T. B., Y. Wang, S. Stukes, Q. Chen, A. Casadevall, and C. Xue. 2011. The F-Box protein Fbp1 regulates sexual reproduction and virulence in Cryptococcus neoformans. Eukaryot Cell 10:791-802

Stukes, S. A., H. W. Cohen, and A. Casadevall. 2014. Temporal kinetics and quantitative analysis of Cryptococcus neoformans nonlytic exocytosis. Infect Immun 82:2059-2067

 
 
 

Wendy Szymczak, Pirofski Lab 

Szymczak, W. A., R. S. Sellers, and L. A. Pirofski. 2012. IL-23 dampens the allergic response to Cryptococcus neoformans through IL-17-independent and -dependent mechanisms. Am J Pathol 180:1547-1559

Szymczak, W. A., M. J. Davis, S. K. Lundy, C. Dufaud, M. Olszewski, and L. A. Pirofski. 2013. X-linked immunodeficient mice exhibit enhanced susceptibility to Cryptococcus neoformans infection. mBio 4

 
 
 

Zoi Tampaki, Kim Lab 

Joyce, B. R., Z. Tampaki, K. Kim, R. C. Wek, and W. J. Sullivan, Jr. 2013. The Unfolded Protein Response in the protozoan parasite Toxoplasma gondii features translational and transcriptional control. Eukaryot Cell 12:979-989

 
 
 

Sangeeta Tiwari, Jacobs Lab 

Junqueira-Kipnis, A. P., F. M. de Oliveira, M. M. Trentini, S. Tiwari, B. Chen, D. P. Resende, B. D. Silva, M. Chen, L. Tesfa, W. R. Jacobs, Jr., and A. Kipnis. 2013. Prime-boost with Mycobacterium smegmatis recombinant vaccine improves protection in mice infected with Mycobacterium tuberculosis. PLoS One 8:e78639

Vilcheze, C., V. Molle, S. Carrere-Kremer, J. Leiba, L. Mourey, S. Shenai, G. Baronian, J. Tufariello, T. Hartman, R. Veyron-Churlet, X. Trivelli, S. Tiwari, B. Weinrick, D. Alland, Y. Guerardel, W. R. Jacobs, Jr., and L. Kremer. 2014. Phosphorylation of KasB regulates virulence and acid-fastness in Mycobacterium tuberculosis. PLoS Pathog 10:e1004115

 
 
 

Julie Wolf, Casadevall Lab 

Wolf, J. M., J. Rivera, and A. Casadevall. 2012. Serum albumin disrupts Cryptococcus neoformans and Bacillus anthracis extracellular vesicles. Cell Microbiol 14:762-773

Robertson, E. J., J. M. Wolf, and A. Casadevall. 2012. EDTA inhibits biofilm formation, extracellular vesicular secretion, and shedding of the capsular polysaccharide glucuronoxylomannan by Cryptococcus neoformans. Appl Environ Microbiol 78:7977-7984

Silva, B. M., R. Prados-Rosales, J. Espadas-Moreno, J. M. Wolf, J. L. Luque-Garcia, T. Goncalves, and A. Casadevall. 2014. Characterization of Alternaria infectoria extracellular vesicles. Med Mycol 52:202-210

Wolf, J., J. Espadas-Moreno, J. L. Luque-Garcia, and A. Casadevall. 2014. Interaction of Cryptococcus neoformans extracellular vesicles with the cell wall. Eukaryot Cell (in press)

 
 
 
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