Einstein/Montefiore Department of Medicine

Continued Treatment for Lupus May Boost Survival of Patients with End-Stage Kidney Disease

October 11, 2011 - Renal & Urology News interviews Dr. Anna Broder about her research that found the chance of survival for lupus patients with end-stage renal disease improved with frequent rheumatologist follow-up and continued immunosuppressive treatment.

September 20, 2011 - (BRONX, NY) - Researchers at Albert Einstein College of Medicine of Yeshiva University have shown that close supervision by rheumatologists and the use of immunosuppressant drugs improve the survival of lupus patients with end-stage kidney disease--a finding that could reverse long-standing clinical practice. Their study appeared in the September 1 online edition of the Journal of Rheumatology.

Anna Broder, M.D.
Anna Broder, M.D.
At least 1.5 million Americans (more than 90 percent of them women) have lupus (officially known as lupus erythematosus), a chronic autoimmune disease that can damage many organs of the body. Treatment usually involves using immunosuppressive drugs to blunt the immune system's attack on the body. Kidney disease is a common complication of lupus, and up to 30 percent of patients with lupus-related kidney disease ultimately develop end-stage renal failure.

"The lupus disease process was thought to become inactive once kidney failure develops," said lead author Anna Broder, M.D., assistant professor of medicine at Einstein.

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