Polycystic Kidney and Liver Diseases: From Gene Discovery to Mechanism
Einstein/Montefiore Department of Medicine Grand Rounds
Thursday, March 13, 2014
8:00 AM: Forchheimer Medical Science Building 3rd Floor Lecture Hall
Speaker & Info
Stefan Somlo, MD
C. N. H. Long Professor of Medicine (Nephrology)
Professor of Genetics
Chief, Section of Nephrology
Yale School of Medicine
Dr. Stefan Somlo's research interests are the genetic bases of human polycystic kidney and liver diseases with the goal of understanding the role cilia and polycystin signaling pathways in both normal adult tissue homeostasis and in progression of cystic diseases. His laboratory has discovered genes for human autosomal dominant polycystic kidney disease (PKD2), isolated polycystic liver disease (PRKCSH, SEC63) and recessive polycystic kidney disease (PKHD1). They have used these discoveries to define both genetic and cellular mechanisms underlying the respective human diseases.
Dr. Somlo is a graduate of Harvard College and the College of Physicians and Surgeons of Columbia University. He completed his clinical training at the Albert Einstein College of Medicine and Yale and was on faculty at Einstein before returning to Yale. He is a member of the American Society for Clinical Investigation and Association of American Physicians for which he is also a Councilor. He is a recipient of the Lillian Jean Kaplan International Prize for Polycystic Kidney Disease Research and the Homer W. Smith Award from the American Society of Nephrology.
Dr. Somlo is the C. N. H. Long Professor of Medicine (Nephrology) and Professor of Genetics and serves as the Chief of the Section of Nephrology at the Yale University School of Medicine.
Objectives - After attending this activity, participants will be able to:
- Clinical features associated with polycystic diseases of the kidney and liver
- The genetic basis and molecular mechanisms underlying cyst formation
- Mechanism based approaches to discovery of novel therapies for polycystic disease
Repeated at 12:15 pm, Cherkasky Auditorium, Montefiore Medical Center.
Accreditation: Albert Einstein College of Medicine designates this educational activity for a maximum of 1 credit towards the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the educational activity.
Division of Nephrology (Department of MEdicine)