Targeting Cardiorenal Endothelins: Clinical Opportunity or Dangerous Venture?
Einstein/Montefiore Department of Medicine Grand Rounds
Thursday, April 04, 2013
8:00 AM: Forchheimer Medical Science Building 3rd Fl Lecture Hall
Speaker & Info
Donald Kohan, MD, PhD
Professor of Medicine
University of Utah School of Medicine
Repeated at 12:15 pm, Cherkasky Auditorium, Montefiore Medical Center
Dr. Kohan received a Ph.D. in Physiology from the University of Minnesota, followed by an M.D. from the University of Miami. He did internal medicine residency and nephrology fellowship training at Washington University, St. Louis, where he joined the faculty in 1987. In 1990 he moved to the University of Utah, where he is currently Professor of Medicine, Physiology and Pharmacology.
Dr. Kohan has served in numerous editorial positions and on NIH and VA study sections. He is a past Chief of Medicine at the Salt Lake VA Medical Center, Chief of Nephrology at the University of Utah, and Dean of Graduate Medical Education at the University of Utah. He is a member of the American Society for Clinical Investigation and the Association of American Physicians. He was the American Society of Nephrology Director of U.S. Nephrology Fellowship Training for six years.
His research for over two decades has focused on kidney regulation of blood pressure and salt balance. He pioneered cell-specific gene targeting in the kidney, and has used these genetically modified mice to identify the role of endothelins and nitric oxide in the control of renal sodium and water transport and blood pressure. His work has been translated to clinical studies, showing promise for using endothelin antagonists to treat kidney disease.
Objectives - After attending this activity, participants will be able to:
- Understand the basic biology of the endothelin system as it pertains to physiology and pathophysiology
- Have insight into clinical trials using endothelin receptor antagonists
- Understand the potential risks and benefits of the clinical use of endothelin receptor antagonists
Accreditation: Albert Einstein College of Medicine designates this educational activity for a maximum of 1 credit towards the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the educational activity.
Division of Nephrology (Department of Medicine)