The dramatic increase in the prevalence of type 2 diabetes in developed and developing countries is causally linked with the geographically and temporally overlapping epidemic of obesity. However, our understanding of how obesity leads to diabetes is still limited. The Einstein Diabetes Research Center has played a central role in the investigation of the basic mechanisms responsible for this association. The basic premise of these studies is that an imbalance between caloric intake and energy expenditure triggers endocrine/metabolic responses that accelerate the age-dependent dysregulation in glucose and lipid metabolism.
Areas of interest include the following:
CNS regulation of glucose/lipid metabolism and feeding behavior?
- Christoph Buettner
- Dongsheng Cai, MD, PhD?
- Streamson Chua, MD, PhD?
- Lloyd Fricker, PhD?
- Roger Gutierez-Juarez, MD, PhD?
- Collette Knight, MD ?
- Young-Hwan Jo, PhD?
- Charles Mobbs
- Gary Schwartz, PhD?
Aging and metabolism: Age- and adiposity-dependent changes in insulin action
- Gil Atzmon, PhD?
- Nir Barzilai, MD?
- Aviv Bergman, PhD?
- Michael Brownlee, MD?
- Jill Crandall, MD?
- Richard Lipton, MD?
- Swapnil Rajpathak, MB, BS, DRPH?
- Clyde Schechter, MD?
- Yousin Suh, PhD?
Peripheral tissue metabolism: systems physiology and molecular integration of whole body metabolism
- Leonard Augenlicht, PhD?
- Jonathan Backer, MD?
- Claire Bastie, PhD?
- Ana Maria Cuervo, MD, PhD?
- Mark Czaja, MD?
- Anna Krook, MD, PhD?
- Irwin Kurland, MD, PhD?
- Zaher Nahle
- Jeffrey Pessin, PhD?
- Jullen Zierath
Glucose sensing and Hypoglycemia ?