Department of Genetics

Computational Genomics Core


The Computational Genomics Core (CGC) supports the Einstein community by providing essential informatics resources and infrastructure for the analysis and interpretation of large genomic and epigenomic datasets, providing for timely and standardized delivery of data to investigators, and to organize and present tutorials for data retrieval and analysis using the provided tools and methodologies. The CGC will develop primary analysis pipelines, analysis and visualization tools for application-specific handling of data using open-source and commercial analysis tools. All tools will be maintained and deployed in a manner that optimally supports the research activities of individual investigators.


  • Data management: storage and delivery of large genomic data sets.
  • Data analysis: primary and secondary interpretation of microarrays and next-generation sequencing data.
  • Pipeline development: assist researchers and core facilities with the development of reproducible, accurate and time-saving pipelines and workflows for analysis of genome-scale experimental data.
  • Consultation: work with investigators to provide access to the appropriate tools for analysis of their data.
  • Training: to aid investigators in the analysis of their own data through tutorials covering software and analysis methodologies.


Individuals will receive a first hour of consultation with a bioinformaticist without charge. Subsequent work will be charged at a rate of $125/hour ($150/hour external). Ongoing or long-term consultation will be eligible for negotiation of a lower hourly rate.


Please visit to self-schedule a walk-in consultation.  You may also submit a work request using our online form: 


Faculty Advisor
John Greally, M.B., PhD

Brent Calder


Selected Publications

R. F. Thompson, M. Suzuki, K. W. Lau, and J. M. Greally. A pipeline for the quantitative analysis of CG dinucleotide methylation using mass spectrometry. Bioinformatics, 25(17):2164–70, Sep 2009.

R. F. Thompson, M. Reimers, B. Khulan, M. Gissot, T. A. Richmond, Q. Chen, X. Zheng, K. Kim, and J. M. Greally. An analytical pipeline for genomic representations used for cytosine methylation studies. Bioinformatics, 24(9):1161–7, May 2008.

R. B. Calder, R. B. Beems, H. van Steeg, I. S. Mian, P. H. M. Lohman, and J. Vijg. MPHASYS: a mouse phenotype analysis system. BMC Bioinformatics, 8:183, 2007.


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News & Events

News | Lan-Hsin Wang and Nicholas Baker paper in Developmental Cell

In a paper recently published in Developmental Cell1, Wang and Baker describes a new function for tumor suppressor genes. read more


News | Dr. Simon Johnson Receives an Award

Dr. Johnson is an American Federation for Aging Research Fellow in the department of Genetics at the Albert Einstein College of Medicine in New York. read more


News | Ozbudak Lab published a new paper in Development

Dr. Ertugrul Ozbudak and his laboratory have published a new paper in the journal, Development. read more

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