Department of Genetics

Publications

Abrahams BS. (2011). Syndromic vs. Idiopathic ASCs. Autism Spectrum Conditions: International Experts answer your Questions on Autism, Asperger syndrome and PDD-NOS. Eds. Hallmayer and Boelte. Hogrefe Press.

Abrahams, B.S., & Geschwind D.H. (2010). Genetics of Autism. Human Genetics: Problems & Approaches. Eds. Speicher, Antonarakiso, and Motulsky. 4th Ed. Springer-Verlag. [ISBN: 9783540376538]

Abrahams, B.S., (2011). Many roads to the Autism Spectrum Disorders. Neuropsychology of Autism. Ed. D. Fein. Oxford Univ Press.

Acosta D SM, Connolly D, Thompson RF, Fazzari MJ, Greally JM and Montagna C: DNA methylation changes in murine breast adenocarcinomas allow the identification of candidate genes for human breast carcinogenesis. Mammalian Genome 2011, 22(3):249.

Agatsuma S, Dang MT, Li Y, Hiroi N. N-methyl-D-aspartic acid receptors on striatal neurons are essential for cocaine cue reactivity in mice. Biol Psychiatry. 67(8):778-80 (2010).

Alkalay AA, Guo T, Montagna C, Digilio MC, Dallapiccola B, Marino B, Morrow B. Genetic dosage compensation in a family with velo-cardio-facial/DiGeorge/22q11.2 deletion syndrome. Am J Med Genet A. 2011 Mar;155A(3):548-54.

Atzmon G, Cho M, Cawthon RM, et al.. Evolution in Health and Medicine Sackler Colloquium: Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians. PNAS, 107(1):1710-1717, 2010.

Atzmon G, Hao L, Pe'er I, Velez C, Pearlman A, Palamara P, Morrow B, Friedman E, Oddoux C, Burns E, Ostrer H. Abraham’s Children in the Genome Era: Major Jewish Diaspora Populations Comprise Distinct Genetic Clusters with Shared Middle Eastern Ancestry. AJHG, 86(6):850–9, 2010.

Atzmon G, Hao L, Pe'er I, Velez C, Pearlman A, Palamara PF, Morrow B, Friedman E, Oddoux C, Burns E, Ostrer H. Abraham’s children in the Genome Era: Major Jewish Diaspora populations comprise distinct genetic clusters with shared Middle Eastern ancestry. Am J Hum Genet. 86:850-9, 2010.

Baker, N.E. (2011). Proximodistal patterning in the Drosophila leg: models and mutations. Genetics, 187 1003-1010.

Baker, N.E. (2011). Cell competition. Curr Biol 21: R11-15.

Baker, N.E., and Firth, L.C. (2011). Retinal Determination Genes function along with cell-cell signals to regulate Drosophila eye development: examples of multi-layered regulation by Master Regulators. Bioessays, 33: 538-546.

Bhattacharya, A. and Baker, N.E. (2011). A network of broadly-expressed HLH genes regulates tissue-specific cell fates. Cell, accepted.

Biswas A, Pasquel D, Tyagi RK, Mani S. Acetylation of Pregnane X Receptor protein determines selective function independent of ligand activation. Biochem Biophys Res Commun. 406(3): 371-6, 2011

Bloom RI, Friedman IB, Chuck RS. Increasing rates of myopia: the long view. Curr Opin Ophthalmol. 21:247-8, 2010.

Brock GJ, Moschos S, Spivack SD, Hurteau GJ. The 3’paradigm of miR-200 family and other microRNAs. Epigenetics, 6:3, 1-5. PMID: 21242719, 2011.

Bryc K, Velez C, Karafet T, Moreno-Estrada A, Reynolds A, Auton A, Hammer M, Bustamante CD, Ostrer H. Genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proc Natl Acad Sci USA. 107 Suppl 2:8954-61, 2010.

Cai G, Atzmon G, Naj A, Beecham GW, Barzilai N, Haines JL, Sano M, Pericak-Vance M, Buxbaum JD. Evidence against a role for rare ADAM10 mutations in sporadic Alzheimer Disease. Neurobiology of Aging, 2010 Apr 7. [Epub ahead of print].

Connolly D, Abdesselam I, Verdier-Pinard P and Montagna C. Septin roles in tumorigenesis. >Biol Chem. 2011 Jul 11. [Epub ahead of print]

Connolly D, Yang Z, Castaldi M, Simmons, N, Oktay MH, Coniglio S, Fazzari MJ, Verdier-Pinard P, Montagna C: Septin 9 isoform expression, localization and epigenetic changes during human and mouse breast cancer progression. Breast Cancer Res 2011 In press.

Cvekl, A., and Mitton, K. 2010. Epigenetic regulatory mechanisms in vertebrate eye development and disease. Heredity 105: 135-151.

D. Moskowitz, B Kosmyna, LE Rogler, B Calder, J Matarlo, R Bebawee, and CE Rogler, Roles for Ago2-RNPs in nuclear and cytoplasmic functions of essential long non-coding RNAs, (2011, manuscript in Review)

Ding J, Yannam GR, Roy-Chowdhury N, Hidvegi T, Basma H, Rennard SI, Wong RJ, Avsar Y, Guha C, Perlmutter DH, Fox IJ, Roy-Chowdhury J. Spontaneous hepatic repopulation in transgenic mice expressing mutant human alpha 1-anti-trypsin by wildtype donor hepatocytes. J. Clin. Invest. 121(5):1930-4, 2011. Pubmed PMID 21505264

Ding J, Yannam GR, Roy-Chowdhury N, Hidvegi T, Basma H, Rennard SI, Wong RJ, Avsar Y, Guha C, Perlmutter DH, Fox IJ, Roy-Chowdhury J. (2011) Spontaneous hepatic repopulation in transgenic mice expressing mutant human alfa 1- antitrypsin by wild-type donor hepatocytes. J Clin Invest.121(5): 1930-1934.

Dou V, Li H, Wang H, Mukherjee S, Kortagere S, Chillimuri SS, Redinbo M, Fearon E, Wang ZT, Mani S. Baicalein Abrogates Inflammation through cdx2/Pregnane X Receptor (pxr) Pathway in a Mouse Model of Chemical Colitis. submitted

Downing, T. E., M. H. Oktay, Fazzari M. and Montagna C. "Prognostic and predictive value of 16p12.1 and 16q22.1 copy number changes in human breast cancer." Cancer Genet Cytogenet 2010 198(1): 52-61.

Erika Pedrosa, Abhishek Shah, Christopher Tenore, Michael Capogna, Catalina Villa, Herbert M. Lachman (2010) Beta-catenin promoter ChiP-chip reveals potential schizophrenia and bipolar disorder gene network. J Neurogenet. 24(4):182-93

Erika Pedrosa, Sashank Kaushik, Herbert M. Lachman (2010) ChIP-chip analysis of candidate genes for addiction susceptibility and neuropsychiatric disorders. J of Neurogenetics 24(1):5-17.

Erika Pedrosa, Vladislav Sandler, Abhishek Shah, Reed Carroll, Chanjung Chang, Shira Rockowitz, Xingyi Guo, Deyou Zheng, Herbert M. Lachman Development of patient-specific neurons in schizophrenia using induced pluripotent stem cells. (in press, Journal of Neurogenetics)

Erin C. Connolly, Koenraad Van Doorslaer, Leslie Rogler, and Charles E. Rogler, Over-expression of micoRNA-21 promotes a metastatic phenotype by targeting the tumor suppressor, RHOB Mol Cancer Res; 8: 691-700, 2010

Faggioli, F., J. Vijg, and Montagna C. "Chromosomal aneuploidy in the aging brain." Mechanisms of ageing and development. >Mech Ageing Dev. 2011 Apr 28. [Epub ahead of print]

Furusho M, Kaga Y, Ishii A, Hebert JM, Bansal R. (2011). FGF Signaling Is Required For The Generation Of Oligodendrocyte Progenitors From The Embryonic Forebrain. J. Neurosci. 31: 5055-5066.

G. Atzmon, M. Cho, R.M. Cawthon, T.. Budagov, M. Katz, X. Yang, G. Siegel, A. Bergman, D.M. Huffman, C.B. Schechter,W.E. Wright, J.W. Shay, N. Barzilai, D.R. Govindaraju, and Y. Suh. Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians. Proc.Natl. Acad. Sci. 107 Suppl(1):1710-1717. 2010

Garcia AM, Calder RB, Dollé ME, Lundell M, Kapahi P, Vijg J. Age- and temperature-dependent somatic mutation accumulation in Drosophila melanogaster. PLoS Genet. 2010;6:e1000950.

Ghosh, R., and Emmons, S. W. (2010) Calcineurin and protein kinase G regulate C. elegans behavioral quiescence during locomotion in liquid. BMC Genetics 11:7.

Goldberg AD, Banaszynski LA, Noh KM, Lewis PW, Elsaesser SJ, Stadler S, Dewell S, Law M, Guo X, Li X, Wen D, Chapgier A, DeKelver RC, Miller JC, Lee YL, Boydston EA, Holmes MC, Gregory PD, Greally JM, Rafii S, Yang C, Scambler PJ, Garrick D, Gibbons R, Higgs DR, Cristea IM, Urnov FD, Zheng D*, Allis CD* (2010). Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell 140:678-691. (*co-corresponding authors)

Gross, SJ, Bajaj, K, Garry, D, Klugman, S, Karpel, BM, Roe, AM, Wagner, B, Zhan, J, Apfelroth, S, and Schreiber-Agus N. (2011). Rapid and novel prenatal molecular assay for detecting aneuploidies and microdeletion syndromes. Pren Diag. 31(3):259-66.

Guo C, Sun Y, Zhou B, Adam RM, Li X, Pu WT, Morrow BE, Moon A, Li X. A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis. J Clin Invest. 2011 Apr 1;121(4):1585-95.

Guo X, Freyer L, Morrow B, Zheng D. (2011) Characterization of the past and current duplication activities in the human 22q11.2 region. BMC Genomics 12:71

Guo X, Freyer L, Morrow B, Zheng D. Characterization of the past and current duplication activities in the human 22q11.2 region. BMC Genomics. 2011 Jan 26;12:71.

Hang, CT, Yang, J, Han, P, Cheng, HL, Shang, C, Ashley, E, Zhou, B, Chang, CP. Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature 466:62-7, 2010

He, S., M. K. Pirity, W.-L. Wang, L. Wolf, B. K. Chauhan, K. Cveklova, E.R. Tamm, R. Ashery-Padan, D. Metzger, P. Chambon, J. Zavadil and A. Cvekl. 2010. Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and their denucleation. Epigenetics & Chromatin 3: 21.

Hongyok T, Kim A, Ladas JG, Jun AS, Chuck RS. Phototherapeutic keratectomy with mitomycin C after Descemet's stripping automated endothelial keratoplasty. Br J Ophthalmol. 94:377-8, 2010.

Hvorecny, K.L. and Prelich, G. (2010) A systematic CEN library of the Saccharomyces cerevisiae genome. Yeast 27:861-865.

Jennifer Cano and Ganjam V. Kalpana. Inhibition of early stages of HIV-1 assembly by INI1/hSNF5 transdominant negative mutant S6. J Virol. 2011 Mar; 85(5):2254-65. Epub 2010 Dec 15.

Jenny, A. (2011), Preparation of adult Drosophila eyes for thin sectioning and microscopic analysis. JoVE, In press.

Kandavel GR, Kang JJ, Memarzadeh F, Chuck RS. Comparison of pterygium recurrence rates in Hispanic and Caucasian patients after primary excision and conjunctival autograft. Cornea. 29:141-5, 2010.

Kerns SL, Ostrer H, Stock RG, Li W, Moore J, Pearlman A, Campbell CL, Shao Y, Stone N, Kusnetz L, Rosenstein BS. Genome wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men following radiotherapy for prostate cancer. Internat J Rad Oncol Biol Phys. 78:1292-1300, 2010.

Kortagere S, Krasowski M, Reschly EJ, Mani S, Ekins S. Computational Docking Preferentially Identified PXR Agonists in the ToxCastTM Database. Environ Health Perspect. 118(10):1412-7, 2010

Krausova L, Stejskalova L, Wang H, Vrzal R, Dvorak Z, Mani S*, Pavek P*. Metformin suppresses nuclear receptor regulated expression of major detoxification enzyme CYP3A4 in human hepatocytes. submitted, * equal contribution, co-senior authors

Kucherlapati M.H., Lee K., Nguyen A.A., Clark A.B., Hou H. Jr., Rosulek A., Li H., Yang K., Fan K., Lipkin M., Bronson R.T., Jelicks L., Kunkel T.A., Kucherlapati R. and Edelmann W. 2010. An Msh2 Conditional Knockout Mouse for Studying Intestinal Cancer and Testing Anti-cancer Agents. Gastroenterology 138:993-1002.

Li, L., C. Greer, R.N. Eisenman and J. Secombe (2010) Essential functions of the histone demethylase Lid. PLoS Genetics 6(11):e1001221.

Louboutin J-P, Chemasova AA, Marusich E, Roy-Chowdhury J, Strayer DS. Efficient CNS gene delivery by intravenous injection. Nature Methods, 7:905-7, 2010. Pubmed PMID 20953176.

Lubensky, D.K., Penninton, M.W., Shraiman, B., and Baker, N.E. (2011). A dynamical model of ommatidial crystal formation. Proc Natl Acad Sci, 108: 11145-11150.

MacColl G.S., Quinton R., Bülow H.E. (2010), Biology of KAL1 and its orthologs: implications for X-linked Kallmann’s syndrome and the search for novel candidate genes. Frontiers of Hormone Research, 39:62-77.

Maier E, von Hofsten J, Nord H, Fernandes M, Paek H, Hébert JM, Gunhaga L. (2010). Opposing activities of FGF and BMP regulate the olfactory sensory versus respiratory epithelial cell fate decision. Development 137: 1601-1611.

Mingyan Lin, Erika Pedrosa, Abhishek Shah, Anastasia Hrabovsky, Shahina Maqbool, Deyou Zheng, Herbert M. Lachman. RNA-Seq of human neurons derived from iPS cells reveals candidate long non-coding RNAs involved in neurogenesis and neuropsychiatric disorders (in press, PLoS One).

Mitra, K, Lenz, J. A combinatorial insulator strategy strongly reduces genome-wide oncogene utilization and tumorigenesis by retroviruses; implications for safer gene therapy. Manuscript submitted.

Moorjani P, Patterson N, Hirschhorn JN, Keinan A, Hao L, Atzmon G, Burns E, Ostrer H, Price AL, Reich D. The history of African gene flow into southern Europeans, Levantines, and Jews. PLoS Genet. 7(4):e1001373, 2011.

Mukherjee S, Wang H, Mani S. Novel physiologic implications for the Pregnane X Receptor in gut innate immunity. submitted

Nakagawa, S., Zhan, J., Sun, W., Ferreira, J.C., Keiles, S., Hambuch, T., Kammesheidt, A., Mark, B., Schneider, A., Gross, S., Schreiber-Agus, N. Platelet Hexosaminidase A enzyme assay effectively detects carriers missed by targeted DNA mutation analysis. Submitted.

Ninkovic, J., L. Pinto, S. Petricca, J. Sun, M.A. Rieger, T. Schroeder, A. Cvekl, J. Favor and M. Gotz. 2010. The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin A. Neuron 68: 682-694.

Özbudak EM, Tassy O, Pourquié O. (2010). Spatiotemporal compartmentalization of key physiological processes during muscle precursor differentiation. Proc Natl Acad Sci USA, 107(9):4224-9.

Paek H, Hwang JY, Zukin RS, Hébert JM. (2011). -catenin-dependent FGF signaling sustains cell survival in the anterior embryonic head by countering Smad4. Developmental Cell 20: 689-699.

Park CY, Chuck RS, Gehlbach PL. The role of indoleamine 2,3 dioxygenase in retinal pigment epithelial cell mediated immune modulation. Ocular Immunol Inflamm. 18:24-31, 2010.

Park CY, Shin YJ, Lekhanont K, Zhang C, Lee WS, Cano M, Bucala R, Chuck RS. High expression of macrophage migration inhibitory factor in the murine lacrimal gland. Cornea. 29:187-91, 2010.

Pataki, C., Matusek, T., Kurucz, E., Andó, I., Jenny, A., Mihály, J. (2010) Drosophila Rab23 is a planar cell polarity gene involved in the regulation of wing hair number. Genetics 184, 1051-1065.

Pearlman, A. Loke J, Le Caignec, C, White, S, Chin L, Friedman A, Warr N, Willan J, Brauer D, Farmer C, Brooks E, Oddoux C, Riley B, Shajahan S, Camerino G, Homfray T, Crosby A, Couper J, David A, Greenfield A, Sinclair A, Ostrer H. Mutations in MAP3K1 cause 46,XY disorders of sex development and implicate a common signal transduction pathway in human testis determination. Am J Hum Genet. 87:898-904, 2010.

Pedrosa E, Shan A, Tenore C, Capogna M, Villa C, Guo X, Zheng D, Lachman HM. ß-catenin promoter ChIP-chip reveals potential schizophrenia and bipolar disorder gene network. J Neurogenet 24: 182-193.

Peñagarikano O, Abrahams BS, Herman EI, Winden KC, Gdalyahu A, Dong H, Sonnenblick LI, Gruver R, Almajano J, Bragin A, Trachtenberg JT, Peles E, Geschwind DH. (2011). "Absence of CNTNAP2 in mice leads to epileptic seizures, ASD-related behavior and atypical neuronal network functioning." In Press at Cell.

Rajpathak SN, Liu J, Ben-David O, Reddy S, Atzmon G, Crandall J, Barzilai N. Lifestyle Factors among People with Exceptional longevity. JAGS. 2011 Aug 3.

Rose AE, Poliseno L, Wang J, Clark M, Pearlman A, Wang G, Vega Y Saenz de Miera EC, Medicherla R, Christos PJ, Shapiro R, Pavlick A, Darvishian F, Zavadil J, Polsky D, Hernando E, Ostrer H, Osman I. Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression. Cancer Res. 71:2561-71, 2011.

Roy-Chowdhury N, Roy-Chowdhury J. (2010) Liver physiology and energy metabolism. In Sleisenger and Fordtran’s Gastrointestinal and Liver Disease, 9th edition.Feldman M, Friedman LS, Brandt LJ, editors. Saunders-Elsevier, Philadelphia. Pp. 1207-1226.

Sanders AE, Wang C, Katz M, Derby CA, Barzilai N, Ozelius L, Lipton RB. Association of a functional polymorphism in the cholesteryl ester transfer protein (CETP) gene with memory decline and incidence of dementia. JAMA. 2010 Jan 13;303(2):150-8. PMID: 20068209

Schechter CB, Barzilai N, Crandall JP, Atzmon G. Reduced Cholesteryl Ester Transfer Protein Levels Is Associated with Decreased Blood Pressure. Mayo Clinic Proceeding, 85(6):522-6, 2010.

Schreiber-Agus, N. (2011) "Clinical Genetic Techniques.” Invited review for book on Genetics and Genetic Diseases: Jewish Legal and Ethical Perspectives, Ed. Deena Cohen Zimmerman, Ktav Publishing House. In Press.

Scott AA, Abrahams BS, Alvarez-Retuerto AI, Sonnenblick LI, Rudie J, Ghahremani D, Mumford J, Poldrack RA, Dapretto M, Geschwind DH, Bookheimer SY. (2010). "Altered Functional Connectivity within the frontal lobe of brain associated with Variation in CNTNAP2." Science Translational Medicine, 3;2(56):56ra80. [PMID: 21048216]

Scott D, Hiroi N. Deconstructing craving: dissociable cortical control of cue reactivity in nicotine addiction. Biol Psychiatry. 69(11):1052-9 (2011).

SeungJae Lee, Velasco Cimica, David Zagzag and Ganjam V. Kalpana. Aurora A Is a Repressed Effector Target of the Chromatin Remodeling Protein INI1/hSNF5 Required for Rhabdoid Tumor Cell Survival. Cancer Res. 2011 May 1;71(9):3225-35. Epub 2011 Apr 26.

Shen HC, Ylaya K, Pechhold K, Wilson A, Adem A, Hewitt SM, Libutti SK. Multiple Endocrine Neoplasia Type 1 Deletion in Pancreatic {alpha}-Cells Leads to Development of Insulinomas in Mice. Endocrinology. 2010 Jun 16. [Epub ahead of print] PubMed PMID: 20555035.

Shin YJ, Tata DB, Waynant RE, Gehlbach PL, Chuck RS. Fluorometric determination of the redox state and distribution of mitochondria in human malignant glioblastoma cells due to different culturing substrates. Photomed Laser Surg. (in press).

Smith ME, Cimica V, Chinni S, Jana S, Koba W, Yang Z, Fine E, Zagzag D, Montagna C, Kalpana GV. Therapeutically targeting Cyclin D1 in primary tumors arising from loss of Ini1. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):319-24. Epub 2010 Dec 20.

Suh, Y. and Vijg, J. The Long and Short of Fertility and Longevity. Cell Metabolism. 12(3):209-210. 2010

Suzuki M, Jing Q, Lia D, Pascual M, McLellan A, Greally JM. Optimized design and data analysis of tag-based cytosine methylation assays. Genome Biol. 2010;11(4):R36. Epub 2010 Apr 1. PubMed PMID: 20359321; PubMed Central PMCID: PMC2884539.

Tazearslan, C., Huang, J., Barzilai, N., and Suh,Y. Impaired IGF1R signaling in cells expressing longevity-associated human IGF1R alleles. Aging Cell. 10(3):551-4. 2011

The Autism Genome Project Consortium. (2010). Functional impact of global rare copy number variation in autism spectrum disorders. Nature. 2010 Jun 9.

The Autism Genome Project Consortium. (2010). A genomewide scan for common alleles affecting risk for autism. Hum Mol Genet. 2010 Jul 27. [PMID: 20663923]

Thompson RF, Atzmon G, Liang HQ, Lowes C, Greally JM, Barzilai N. Tissue-specific dysregulation of DNA methylation in aging. Aging cell, 9(4):506-18, 2010.

Thompson RF, Fazzari MJ, Niu H, Barzilai N, Simmons RA, Greally JM. Experimental intrauterine growth restriction induces alterations in DNA methylation and gene expression in pancreatic islets of rats. J Biol Chem. 2010 May 14;285(20):15111-8. Epub 2010 Mar 1. PubMed PMID: 20194508; PubMed Central PMCID: PMC2865297.

Tornberg J., Keefe K., Sykiotis G.P., Plummer L., Hoang X, Hall J., Quinton R., Seminara S., Hughes V., Van Vliet G., Van Uum S., Crowley, Jr W.F., Habuchi H., Kimata K., Pitteloud N.*, Bülow H.E.* (2011) Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism. PNAS, 108(28):11524-11529.

Townley R.A., and Bülow H.E. (2011) Genetic Analysis of the Heparan modification network in Caenorhabditis elegans. J. Biol. Chem., 286(19):16824-31, published online March 24, 2011 as doi:10.1074/jbc.M111.227926.

van Oers J.M., Roa S., Werling U., Liu Y., Genschel J., Hou H. Jr., Sellers R.S., Modrich P., Scharff M.D., Edelmann W. 2010. PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance. Proc Natl Acad Sci U S A. (in press)

Venkatesh M, Wang H,Cayer J, Leroux M, Salvail D, Das B, Mani S. Designing First-In Class Novel and Non-Toxic Azole Analogs that Target Pregnane X Receptor (PXR)-Mediated Drug Resistance. Mol Pharm, In press 2011

Wallace B, Wang H, Lane KT, Scot JE, Oran E, Koo J, Jobin C, Yeh L, Mani S, Redinbo M. Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme. Science. 330(6005):831-5, 2010

Walter S, Atzmon G, Demerath EW, et. al. Neurobiol Aging. 2011 Jul 20. [Epub ahead of print]

Wang H, Venkatesh M, Hao L, Goetz R, Mukherjee S, Biswas A, Zhu L, Kaubisch A, Wang L, Pullman J, Whitney K, Kuo-o M, Roig AI, Mohammadi M, Mani S. Pregnane X Receptor Activation Leads to Fibroblast Growth Factor-19 Dependent Tumor Regeneration after Cancer Chemotherapy. J. Clin Invest, In press 2011

Wang Y., Zhang W., Edelmann L., Kolodner R.D., Kucherlapati R. And Edelmann W. 2010. Cis lethal genetic interactions attenuate and alter p53 tumorigenesis. Proc Natl Acad Sci U S A 107:5511-5515. PMID: 20212136

Warr N, Bogani D, Siggers P, Brixey R, Tateossian H, Dopplapudi A, Wells S, Cheeseman M, Xia Y, Ostrer H, Greenfield A. Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1. PLoS One. 6(5):e19572, 2011.

Wontakal SN, Guo X, Will B, Shi M, Raha D, Mahajan MC, Weissman S, Snyder M, Steidl U, Zheng D*, Skoultchi AI*. (2011) A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1. PLoS Genet 7:e1001392. (*co-corresponding authors)

Wu, B., Wang, Y., Lui, W., Langworthy, M., Tompkins, K.L., Hatzopoulos, A.K., Baldwin, H.S., Zhou, B. Nfatc1 Coordinates Valve Endocardial Cell Lineage Development Required for Heart Valve Formation. Circ. Res. 2011 May 19 [Epub ahead of print]

Wu, B., Zhou, B., Wang, Y., Cheng, H-L, Hang, C.T., Pu, W.T., Chang, C-P and Zhou, B. Inducible cardiomyocyte-specific gene disruption directed by the rat Tnnt2 promoter in the mouse. Genesis 48:63-72, 2010

Yang, C., Y. Yang, L. Brennan, E. E. Bouhassira, M. Kantorow and A. Cvekl. 2010. Efficient generation of lens progenitor cells and lentoid bodies from human embryonic stem cells in chemically defined conditions. FASEB J. 24: 3274-3283.

Zeegers MP, Khan HS, Schouten LJ, van Dijk BA, Goldbohm RA, Schalken J, Shajahan S, Pearlman A, Oddoux C, van den Brandt PA, Ostrer H. Genetic marker polymorphisms on chromosome 8q24 and prostate cancer in the Dutch population: DG8S737 may not be the causative variant. Eur J Hum Genet. 19:118-20, 2011.

Zhang ZD, Frankish A, Hunt T, Harrow J, Gerstein M. (2010) Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates. Genome Biol., 11, R26.

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