Department of Genetics

Translational Genetics

Division Chief: Bernice E. Morrow, PhD

Human genetics is the centerpiece of translational research. The main goal is to identify DNA sequence or copy number variation and epigenomic alterations that alter risk to common human diseases. The first step requires recruitment of human subjects from our local hospitals including Montefiore Medical Center and Jacobi Hospital. This will be followed by molecular genetic studies identifying disease related genes.

Once genes or molecular mechanisms are identified, novel lab diagnostics will be set up and validated in the research lab. Application of genetic testing in the clinic will provide a diagnosis for families. This will provide their clinicians the tools to advise families both in regards to prenatal diagnostics and for the latest care of individuals with the particular disorder. Novel clinical lab findings can be translated back to the research arena. Human cohort research combined with studies in animal models and back again provide a complete circle for improving health care.

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News & Events

News | Papers Published in Developmental Cell and eLife

Hannes Buelow and members of his laboratory have had papers published in Developmental Cell and eLife. read more

 

News | Paper Published in Developmental Cell

Nick Baker's laboratory has published a paper in Developmental Cell. read more

 

News | Review on bHLH transcription factors

Review on bHLH transcription factors regulating neuronal development and neuronal diversity. read more

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