Department of Biochemistry

Scientific Instrumentation and Resources

Department Office

Department of Biochemistry
Albert Einstein College of Medicine
1300 Morris Park Avenue
Forchheimer 308
Bronx, NY 10461-1602

Telephone: 718.430.2814
Fax: 718.430.8565
General Email: biochemistry@einstein.yu.edu 

 

Travel Directions: 

Follow the directions to the college.

The Department of Biochemistry houses and manages an extensive array of scientific instrumentation and equipment to study biological molecules. Specialized equipment can also be found in many of the research laboratories.

  • An NMR facility housing both a 600 MHz and 300 MHz nuclear magnetic resonance spectrometer.  Access to the New York Stuctural Biology Center which houses several 800 MHz NMR spectrometers with cryo-probes.
  • Access to synchotron radiation at the Brookhaven National Laboratory is through beamlines X4 and X29 for X-ray crystallography, EXAFS, and X-ray footprinting experiments.  In addition, a rotating anode x-ray generator and area detector is available for the rapid collection of diffraction data.
  • The Laboratory for Macromolecular Analysis & Proteomics (LMAP, or Proteomics Core) provides a comprehensive mass spectrometry resource for analysis of proteins, peptides, carbohydrates, lipids & unknowns for Einstein researchers.
    • MALDI-TOF, ESI-, and FT-ICR mass spectrometry; 2D-gels, 2D-DIGE, & high resolution HPLC
    • Rapid turnaround time for protein ID from gel bands. Protein identification of proteins from gel bands, immunoaffinity isolations, or specialty preparations.
    • protein complexes, identification of components
    • posttranslational modifications
    • protocols & tips for optimal sample preparation; training in methods, data acquisition, data analysis
    • quantitative proteomics by SILAC, SILAM, 18O, iTRAQ, & label-free methods
    • hydrogen/deuterium exchange-mass spectrometry for studies of protein dynamics & biomolecular interactions
    • confirmation of synthetic & recombinant molecules  
    • high resolution analysis by FT-ICR-MS of metabolites, drugs, peptides & small molecules
     
  • Macromolecular Therapeutics Development 
  • UNIX and Linux workstations for molecular modeling and other computational analyses.

The college has numerous other resources available to all basic scientists including:

Click here to log in