Allan W. Wolkoff, MD
Professor (Medicine and Anatomy and Structural
The Liver Cell Membrane Proteins: Expression and Function Program Project focuses on functions and trafficking of specific liver cell membrane proteins. The studies (projects) comprising this program represent multidisciplinary approaches to several fundamental questions in liver pathobiology.
All four Projects are concerned with interrelated areas of hepatocyte membrane biology and pathobiology, and each proposed project represents collaborative efforts between independent investigators.
- Project 1: Control of Vesicular Trafficking in the Hepatocyte
Principal Investigator: Allan W. Wolkoff, M.D.
- Project 2: Expression, Processing, and Function of Liver Gap Junctions
Principal Investigator: David C. Spray, Ph.D.
- Project 3: Genetic Analysis of Liver Membrane Protein Traffic
Principal Investigator: Pamela Stanley, Ph.D.
- Project 4: Interaction of Autophagic and Heterophagic Pathways in Liver Principal Investigator: Ana Maria Cuervo, M.D., Ph.D.
- Core A: Administrative and Supporting Services Core
Provides secretarial, bookkeeping, and common equipment functions.
- Core B: Molecular Cytology Core
Provides state-of-the-art microscopy and imaging services.
- Core C: Proteomics Core
Facilitates the substantial use of this technology by each of the four Projects.
Allan W. Wolkoff, M.D., Program Director
Ruth H. Angeletti, Ph.D.
Ana Maria Cuervo, M.D., Ph.D.
John W. Murray, Ph.D.
Phyllis M. Novikoff, Ph.D.
David L. Silver, M.D., Ph.D.
Erik L. Snapp, Ph.D.
David C. Spray, Ph.D.
Pamela Stanley, Ph.D.
Duncan W. Wilson, Ph.D.
Peter Satir, Ph.D.