Einstein-Rockefeller-CUNY Center for AIDS Research

Clinical, Translational and Implementation Science Core

The overarching goal of the ERC-CFAR’s Clinical, Translational and Implementation Science Core (CTISC) is to provide a regional research platform to support the initiation and expansion of HIV-related clinical, translational and implementation research. The CTISC will assist researchers in participant recruitment for both clinical trials (e.g. eradication research or pathogenesis) and for observational studies by active recruitment of patients with rare phenotypes (e.g. elite or viremic controllers) for studies anywhere in the United States. It also provides support for research projects assessing policy, contextual, clinic/practice and individual factors impacting uptake and outcomes of delivered services, and access to and analysis of data from three databases.

The CTISC provides access to three robust clinical databases. The Clinical Cohort, from the Montefiore/Einstein clinical services, has over 16,000 HIV-infected and 285,000 HIV-negative patients. This dynamic, comprehensive, longitudinal database accesses Montefiore’s extensive clinical infrastructure to facilitate enrollment of well-characterized patients (including HIV-negative controls) into new research protocols. The Amida Care Cohort leverages the informatics resources of Amida Care, the largest Medicaid Special Needs Plan in NYS, with >6,000 PLWH in NYC. The Master Research Cohort has centralized data and specimen information from ~4700 participants in 31 funded research studies. With seed funding from Einstein, these three resources have stimulated many new clinical, implementation and translational investigations within Einstein, with the primary partners (Rockefeller and CUNY) and with other investigators in NYC and nationally. The maintenance of the Clinical Cohort Database succeeds through collaboration with Einstein’s Institute for Clinical and Translational Research (ICTR), an NIH-funded site in the Clinical and Translational Science Awards (CTSA) program, and its integration into the ICTR’s Informatics Commons. CTISC maintains an infrastructure to facilitate recruitment and enrollment from all three cohorts into clinical trials, observational and translational studies requiring new specimens or special studies (e.g. functional MRI) in HIV-infected individuals with specified clinical characteristics.

  • Provide a clinical research platform to serve basic, clinical/epidemiologic, translational, behavioral and implementation science investigators in New York City or beyond. We will
    • Leverage our large patient population of 16,198 PLWH seen since 1997 with >91,000 person-years of follow-up to catalyze new research and recruit participants for investigators conducting clinical trials or other studies.
    • Use state-of-the-art informatics provided through Einstein’s ICTR to maintain databases derived from Montefiore/ Einstein’s integrated electronic health informatics system and Amida Care to support new investigations in diverse, underrepresented groups (e.g. women, pregnancy, MSM of color, HIV-exposed) through support in study design, biostatistics, database access and specimen collection.
    • Integrate with the ERC-CFAR’s Behavioral Science Core and the Scientific Working Groups (Eradication, Patient and Population Health Outcomes Research ) to support the entire ERC-CFAR’s scientific goals.
  • Advance collaboration under the umbrella of implementation science
    • Support research to identify multi-level factors that influence timely and sustained achievement of HIV Care/Prevention Continuum outcomes (e.g. uptake of PrEP, early diagnosis, sustained viral suppression) in specific populations.
  • Support bench scientists in translational investigation (e.g. virologic, immunologic, genetic) studies
    • Provide human specimens, both through the existing research and clinical biorepositories (Master Research Cohort), and through rapidly sourcing, enrolling and consenting patients with specific characteristics, assisting in IRB approval, and supporting fresh specimen collection, transport and processing.
  • For further information or to access the CT ISC services, please contact Drs. Anastos, CaskeyStricklerJones.

Dr. Kathy Anastos
Director, ERC Clinical Translational and Implementation Science Core, Einstein
Professor, Medicine, Epidemiology & Population Health, Obstetrics & Gynecology and Women's Health
Co-Director, Global Health Center  

Dr. Marina Caskey
Associate Director, Clinical Research Studies
Assistant Professor, Clinical Investigation, Rockefeller
Member, Laboratory of Molecular Immunology


Dr. Howard Strickler
Associate Director, Epidemiologic Studies
Professor, Dept. of Epidemiology & Population Health, Einstein
Harold and Muriel Block Chair, Epidemiology & Population Health
Division Head, Div of Epidemiology

Dr. Heidi Jones
Associate Director, Implementation Science
Assistant Professor,Epidemiology, CUNY School of Public Health and Hunter College


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ERC-CFAR at a Glance

Partner Institutions 

  • Albert Einstein College of Medicine
  • Rockefeller University
  • The City University of New York (CUNY)


Total ERC-CFAR members

  • 183 Full members
  • 10 Affiliate members

CFAR member trainees funded by NIH K awards

  • 15 Full members

NIH Funding 

FY2015 OAR NIH AIDS FRB grants

$34,084,840 Total costs


New NIH AIDS grants awarded in FY2016

$7,345,645 Total annual costs


FY2014 non-AIDS NIH grants

$34,745,334 Total costs

Publications (first 6 months of 2016) 

Total Publications: 240

Publications multi-authored
by ERC-CFAR members: 91



Director: Dr. H. Goldstein



Directors: Dr. V. Prasad & Dr. C. Cunningham


Biomarkers & Advanced Technologies 

Directors: Dr. J. Berman & Dr. S. Almo


Behavioral Science 

Director: Dr. L. Bauman


Clinical Translational Implementation Science 

Director: Dr. K. Anastos


Scientific Working Groups 

HIV and Eradication 

Directors: Dr. G. Kalpana & Dr. M. Caskey


Patient and Population Health Outcomes Research 

Directors: Dr. D. Nash & Dr. J. Arnsten  

New 2016 NIH Grants Awards 

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In the Media

Vice interviews Harris Goldstein, M.D., about the difficulty of developing a vaccine for HIV. Dr. Goldstein is professor of pediatrics and of microbiology & immunology at Einstein and director of the Einstein-Rockefeller-CUNY Center for AIDS Research. (Wednesday, Aug 30, 2017)

Crain’s Health Pulse interviews Dr. Laurie Bauman regarding a collaborative study aimed at controlling the spread of HIV using PrEP, a drug proven to reduce risk. Dr. Bauman is a principal investigator on the study, which includes Einstein, Montefiore and Columbia. She also is director of the Preventive Intervention Research Center and professor of pediatrics. (Friday, Jul 29, 2016)

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