Center for AIDS Research

About the Einstein-Montefiore CFAR

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As a direct consequence of the emergence of the Bronx as one of the initial epicenters of the HIV epidemic, Einstein and Montefiore investigators have been at the forefront of HIV/AIDS research since the first descriptions of HIV infection over 25 years ago. HIV continues to have a devastating impact on the Bronx population. Some Bronx neighborhoods currently have an HIV prevalence that is greater than several African countries including Ethiopia, Rwanda and Nigeria. Almost 24,000 individuals identified as being HIV-infected in the Bronx of whom almost 40% are women and over 85% are Black or Hispanic. It is estimated that there are an additional 6,000 HIV-infected Bronx residents who are unaware they are infected and frequently do not learn they are HIV-infected until they present with full-blown AIDS. Montefiore is integrally involved in HIV patient care in the Bronx, and Montefiore-affiliated sites and provides care for nearly 15,000 of the HIV-infected patients in the Bronx.

The Einstein-Montefiore Center for AIDS Research (CFAR) supports and coordinates the research efforts of more than 120 NIH-funded Einstein faculty members from 16 basic and clinical departments whose basic and translational research programs are focused on a variety of aspects of the pathophysiology, manifestations and treatments of HIV infection and its sequelae. The CFAR oversees eight core facilities which provide a wide range of facilities, technologies and services to support basic science, translational and clinical research activities at the Einstein and Montefiore. More information about the NIH CFAR program, Einstein-Montefiore CFAR, Einstein-Montefiore AIDS investigators and their research programs, the Einstein NIH-funded AIDS training program can be found by clicking on the links above. The leadership and infrastructure provided by the Einstein-Montefiore CFAR drives and supports the innovative basic science, translational and clinical research of Einstein HIV/AIDS investigators, particularly their efforts to develop, establish and evaluate interdisciplinary basic, clinical and translational research approaches to prevent new HIV infections, a persistent problem that drives expansion of the HIV epidemic in the Bronx, and in other HIV epicenters in the U.S. and the world. The CFAR also supports the highly diverse HIV/AIDS-related research activities of CFAR members investigating the pathogenesis of HIV infection, and developing new approaches to tackle emerging scientific questions at the cutting-edge of HIV/AIDS research, particularly those identified in the OAR’s Trans-NIH Plan for HIV Research.

Through our integrative strategic planning process, the Einstein-Montefiore CFAR leaders and members have identified a set of specific aims to guide and support our research efforts:

  1. To lead a highly interdisciplinary and coordinated effort to develop, implement and evaluate new approaches to prevent HIV infections.
  2. To engage with the Bronx community through the CFAR Community Advisory Board to identify approaches that optimize diagnosis, treatment and prevention of HIV infection, particularly in the underserved populations with limited access to care and illicit drug users who are at high risk for reduced adherence to treatment and increased rates of transmission and acquisition.
  3. To provide scientific leadership and an Institutional infrastructure across basic science and clinical departments to actively stimulate interdisciplinary, collaborative and translational research among basic science, epidemiological, clinical and behavioral investigators at Einstein and other New York City Medical Centers.
  4. To use established and highly responsive shared scientific Core facilities to drive innovative multidisciplinary research and enable Einstein-Montefiore CFAR investigators to efficiently and economically utilize the unique services required for HIV research.
  5. To provide intellectual, technical and financial support to mentor and advance the careers of the next generation of young, innovative and interdisciplinary HIV/AIDS MD, PhD, and MD/PhD investigators.
  6. To support the capacity of international sites to develop and expand HIV prevention and treatment programs as well as indigenous research by sharing the knowledge and expertise gained by Einstein and Montefiore AIDS researchers who care for the diverse underserved, hard-to-reach and marginalized HIV-infected and at-risk population in the Bronx.

To drive research by CFAR investigators to achieve these Aims while stimulating new creative and interdisciplinary approaches, we established three Research Programs:

Substance Abuse & HIV Transmission- Co-directed by Drs. Julia Arnsten and Aaron Fox is focused on determining mechanisms by which substance abuse facilitates HIV transmission and how to optimize HIV prevention and treatment in individuals who are substance abusers and meets monthly in the DGIM Conference Room, 3514 Dekalb Avenue. 

HIV Transmission to Women- Co-directed by Drs. Betsy Herold and Rebecca Madan is focused on identifying factors unique to the pathogenesis, treatment and course of HIV infection in women and meets monthly with the Einstein-Montefiore Transdisciplinary Center to Promote Women/Infant Health and Disease Eradication (EMPOWER) group in Price 351 on the second Monday of the month from 8:30AM-10:00AM. 

HIV and Mtb Co-infection- Co-directed by Drs. William Jacobs and James Brust is focused on delineating the pathogenic interactions between HIV and TB that impact on HIV transmission, diagnosis, treatment and disease course and meets on the first Monday of the month in Price 557 from 9:00AM-10:00AM. 

 

 

Phone: 718.430.2156
Fax: 718.430.2374
Address: 1300 Morris Park Avenue, Bronx, NY 10461
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