As a direct consequence of the
emergence of the Bronx as one of the initial epicenters of the HIV epidemic,
Einstein and Montefiore investigators have been at the forefront of HIV/AIDS
research since the first descriptions of HIV infection over 25 years ago. HIV
continues to have a devastating impact on the Bronx population. Some Bronx
neighborhoods currently have an HIV prevalence that is greater than several
African countries including Ethiopia, Rwanda and Nigeria. Almost 24,000
individuals identified as being HIV-infected in the Bronx of whom almost 40%
are women and over 85% are Black or Hispanic. It is estimated that there are an
additional 6,000 HIV-infected Bronx residents who are unaware they are infected and
frequently do not learn they are HIV-infected until they present with
full-blown AIDS. Montefiore is integrally involved in HIV patient care in the
Bronx, and Montefiore-affiliated sites and provides care for nearly 15,000 of the
HIV-infected patients in the Bronx.
The Einstein-Montefiore Center for
AIDS Research (CFAR) supports and coordinates the research efforts of more than
120 NIH-funded Einstein faculty members from 16 basic and clinical departments whose
basic and translational research programs are focused on a variety of aspects
of the pathophysiology, manifestations and treatments of HIV infection and its
sequelae. The CFAR oversees eight core facilities which provide a wide range of
facilities, technologies and services to support basic science, translational
and clinical research activities at the Einstein and Montefiore. More
information about the NIH CFAR program, Einstein-Montefiore CFAR,
Einstein-Montefiore AIDS investigators and their research programs, the
Einstein NIH-funded AIDS training program can be found by clicking on the links
leadership and infrastructure provided by the Einstein-Montefiore CFAR
drives and supports the innovative basic science, translational and clinical
research of Einstein HIV/AIDS investigators, particularly their efforts to
develop, establish and evaluate interdisciplinary basic, clinical and
translational research approaches to prevent new HIV infections, a persistent
problem that drives expansion of the HIV epidemic in the Bronx, and in other
HIV epicenters in the U.S. and the world. The CFAR also supports the highly diverse HIV/AIDS-related research
activities of CFAR members investigating the pathogenesis of HIV infection, and
developing new approaches to tackle
emerging scientific questions at the cutting-edge of HIV/AIDS research,
particularly those identified in the OAR’s Trans-NIH Plan for HIV Research.
our integrative strategic planning process, the Einstein-Montefiore CFAR
leaders and members have identified a set of specific aims to guide and support
our research efforts:
- To lead a highly interdisciplinary and
coordinated effort to develop, implement and evaluate new approaches to prevent
- To engage
with the Bronx community through the CFAR Community Advisory Board to identify
approaches that optimize diagnosis, treatment and prevention of HIV infection,
particularly in the underserved populations with limited access to care and
illicit drug users who are at high risk for reduced adherence to treatment and
increased rates of transmission and acquisition.
provide scientific leadership and an Institutional infrastructure across basic
science and clinical departments to actively stimulate interdisciplinary,
collaborative and translational research among basic science, epidemiological,
clinical and behavioral investigators at Einstein and other New York City
- To use
established and highly responsive shared scientific Core facilities to drive
innovative multidisciplinary research and enable Einstein-Montefiore CFAR
investigators to efficiently and economically utilize the unique services
required for HIV research.
provide intellectual, technical and financial support to mentor and advance the
careers of the next generation of young, innovative and interdisciplinary HIV/AIDS
MD, PhD, and MD/PhD investigators.
support the capacity of international sites to develop and expand HIV
prevention and treatment programs as well as indigenous research by sharing the
knowledge and expertise gained by Einstein and Montefiore AIDS researchers who
care for the diverse underserved, hard-to-reach and marginalized HIV-infected
and at-risk population in the Bronx.
To drive research by
CFAR investigators to achieve these Aims while stimulating new creative and
interdisciplinary approaches, we established three Research Programs:
Substance Abuse &
HIV Transmission- Co-directed
by Drs. Julia Arnsten and Aaron Fox is focused on determining mechanisms by
which substance abuse facilitates HIV transmission and how to optimize HIV
prevention and treatment in individuals who are substance abusers and meets monthly in the DGIM Conference Room, 3514 Dekalb Avenue.
HIV Transmission to
by Drs. Betsy Herold and Rebecca Madan is focused on identifying factors unique
to the pathogenesis, treatment and course of HIV infection in women and meets monthly with the Einstein-Montefiore Transdisciplinary Center to Promote Women/Infant Health and Disease Eradication (EMPOWER) group in Price 351 on the second Monday of the month from 8:30AM-10:00AM.
and Mtb Co-infection- Co-directed by Drs.
William Jacobs and James Brust is focused
on delineating the pathogenic interactions between HIV and TB that impact on
HIV transmission, diagnosis, treatment and disease course and meets on the first Monday of the month in Price 557 from 9:00AM-10:00AM.
Address: 1300 Morris Park Avenue, Bronx, NY 10461
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