Longevity Genes Project

Understanding genetic factors leading to exceptionally long life

Become part of Albert Einstein College of Medicine's Institute for Aging Research study.
Help us better understand healthy aging and preventing age-related diseases.

Become a participant in phase 2
Learn more about Phase 1 Watch participant video Watch participant video Become part of Phase 2

Hear more from Dr. BarzilaiWith funding from the National Institute of Aging and the Glenn Foundation, Dr. Nir Barzilai is leading the research project to determine the role of genes in exceptional longevity.

Hear more from Dr. Barzilai

 

Phase 1 Findings

  • Longevity is highly correlated to high HDL ("good") and low LDL ("bad") cholesterol levels
  • Mutations in cholesterol genes are associated with longevity and the prevention of cognitive decline and Alzheimer's disease
  • Mutations in a growth hormone gene is associated with longevity
  • Subjects with a certain genetic makeup live on average 4 years longer than those without
  • Longevity is highly likely to be inherited from generation to generation

    Longevity Genes Project Website

Longevity Media Coverage

Wall Street Journal features new research by Nir Barzilai, M.D. that found lower levels of growth hormone are associated with extended lifespan in centenarians. Concerns about the dangers of using human growth hormone (HGH) as an anti-aging agent—a growing $4 billion industry—are increasing. Dr. Barzilai notes hormones that might have some beneficial effect for children with stunted growth may have a negative effect on aging adults. Dr. Barzilai is the Ingeborg and Ira Leon Rennert Chair of Aging Research and director of Einstein's Institute for Aging Research.

Dr. Nir Barzilai

“I hope that in our lifetime, we’ll be able to use medicine in order to prevent age-related diseases and improve our quality of life. I think it's our obligation as scientists to do that.”

– Nir Barzilai, M.D.

Are You Interested in Joining the Study?

We are currently recruiting participants for phase 2. If you are 65 years or older, at least one parent lived to 95 or older, and are of Ashkenazi Jewish descent, click here to learn more.

Become a participant in phase 2

Click here to log in Institute for Aging Research

The Longevity Genes Project

Nir Barzilai, M.D.

In the Longevity Genes Project at Albert Einstein College of Medicine, Dr. Nir Barzilai and his team conducted genetic research on more than 500 healthy elderly people between the ages of 95 and 112—and on their children.

The identification of longevity genes by Einstein researchers could lead to new drug therapies that might help people live longer, healthier lives and avoid or significantly delay age-related diseases such as Alzheimer’s disease, type 2 diabetes and cardiovascular disease.

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Contact Us

Director 

Nir Barzilai, MD
Ingeborg and Ira Leon Rennert Chair of Aging Research
Professor of Medicine and Genetics
Director, Institute for Aging Research
(718) 430-3144
Fax: (718) 430-8557
nir.barzilai@einstein.yu.edu 

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