Longevity Genes Project

Understanding genetic factors leading to exceptionally long life

Become part of Albert Einstein College of Medicine's Institute for Aging Research study.
Help us better understand healthy aging and preventing age-related diseases.

Become a participant in phase 2
Learn more about Phase 1 Watch participant video Watch participant video Become part of Phase 2

Hear more from Dr. BarzilaiWith funding from the National Institute of Aging and the Glenn Foundation, Dr. Nir Barzilai is leading the research project to determine the role of genes in exceptional longevity.

Hear more from Dr. Barzilai


Phase 1 Findings

  • Longevity is highly correlated to high HDL ("good") and low LDL ("bad") cholesterol levels
  • Mutations in cholesterol genes are associated with longevity and the prevention of cognitive decline and Alzheimer's disease
  • Mutations in a growth hormone gene is associated with longevity
  • Subjects with a certain genetic makeup live on average 4 years longer than those without
  • Longevity is highly likely to be inherited from generation to generation

    Longevity Genes Project Website

Longevity Media Coverage

Bloomberg News interviews Nir Barzilai, M.D., about Novartis’ efforts to develop FDA-approved drug rapamycin as an anti-aging, preventative therapy. It was long believed that rapamycin suppressed the immune response, rendering it unsuitable for long-term use in older adults. However, Dr. Barzilai notes that a recent “watershed” moment occurred when new research found it merely modulated the immune response in humans, clearing the way for more research. Dr. Barzilai is the Ingeborg and Ira Leon Rennert Chair of Aging Research and director of the Institute for Aging Research at Einstein and attending physician at Montefiore Medical Center.

Dr. Nir Barzilai

“I hope that in our lifetime, we’ll be able to use medicine in order to prevent age-related diseases and improve our quality of life. I think it's our obligation as scientists to do that.”

– Nir Barzilai, M.D.

Are You Interested in Joining the Study?

We are currently recruiting participants for phase 2. If you are 65 years or older, at least one parent lived to 95 or older, and are of Ashkenazi Jewish descent, click here to learn more.

Become a participant in phase 2

Click here to log in Institute for Aging Research


Nir Barzilai aging research albert einstein college of medicine Montefiore Medical Center Bronx NYNir Barzilai, MD (bio) 

Professor of Medicine
Professor of Genetics
Ingeborg and Ira Leon Rennert Chair in Aging Research

From the Director 


Contact Us

Aging Research Center
Albert Einstein College of Medicine
Belfer 701
1300 Morris Park Avenue
Bronx, NY 10461

(718) 430-3144
Fax: (718) 430-8557