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Services

Procedures/measurements currently offered:

• Reperfused myocardial infarction experiments (open-chest and closed-chest models of murine coronary ischemia/reperfusion)

• Non-reperfused myocardial infarction experiments (permanent coronary occlusion)

• Experimental models of cardiac hypertrophy and fibrosis in the mouse (model of transverse aortic constriction, model of cardiac fibrosis due to brief repetitive coronary occlusion/reperfusion)

• Assessment of cardiac systolic and diastolic function using 2D-echocardiography and invasive hemodynamic monitoring

• Assessment of cardiac remodeling to study the geometric alterations of the ventricle following cardiac injury using echocardiography (M-mode and two-dimensional) and quantitative morphometry

• Insertion of arterial (e.g. carotid) and venous (e.g. jugular) catheters for blood pressure measurements,drug infusion,or cell therapy.Tail vein injections.

• Implantation of osmotic minipumps for drug infusion (e.g. Alzet)

*Contact Core staff to determine the availability of new surgical and measurement services being developed .

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Contacts

Scientific Director
Nikolaos G. Frangogiannis, M.D.
718.430.3546
nikolaos.frangogiannis@einstein.yu.edu

Operations Director
Zhiping (David) Wu, M.D.
718.430.4141
zhiping.wu@einstein.yu.edu