Proteomics (LMAP)

Overview

The Proteomics Facility, supported by the Laboratory for Macromolecular Analysis and Proteomics (LMAP), provides Einstein researchers with a comprehensive mass spectrometry resource for analysis of proteins, peptides, carbohydrates, lipids and unknowns. Expert staff scientists are available to help plan and execute a successful proteomics based analysis.

Services

  • MALDI-TOF, ESI- and FT-ICR mass spectrometry; 2D-gels, 2D-DIGE and high-resolution HPLC
  • Rapid turnaround time for protein ID from gel bands, immunoaffinity isolations or specialty preparations
  • Identification of components of protein complexes
  • Posttranslational modifications of proteins
  • Spatial localization of  molecules by imaging (in situ) mass spectrometry
  • Protocols and training in methods, data acquisition, data analysis
  • Quantitative proteomics using SILAC, SILAM, 18O, iTRAQ and label-free methods
  • Study of protein dynamics and biomolecular interactions using hydrogen/deuterium exchange-mass spectrometry
  • Confirmation of synthetic and recombinant molecules
  • High-resolution analysis by FT-ICR-MS of metabolites, drugs, peptides and small molecules
  • MRM assays and pharmacokinetics

Location and Contacts

Proteomics (LMAP)

Ullmann 403

 
 
 

Scientific Director
Ruth Hogue Angeletti, Ph.D.
718.430.3475
ruth.angeletti@einstein.yu.edu

Operations Director
Edward Nieves
718.430.3476
edward.nieves@einstein.yu.edu