Research Profiles

Scientific Discovery

John M. Greally, M.B.,B.Ch., Ph.D.

Gene Expression: Turning Diseases On & Off

John Greally, M.B., B.Ch., Ph.D., Einstein’s Faculty Scholar for Epigenomics, studies chemicals that attach to genes and affect their expression. Dr. Greally’s research has led to a better understanding of the epigenetic regulation of stem cells and of the epigenetic abnormalities that underlie human diseases, including breast cancer, diabetes, Huntington’s disease, allergies and autism. His recent epigenetic research has suggested a role for environmental factors in autism. Since epigenetic changes are reversible, his work could lead to novel therapies.

Dr. Greally, a professor of genetics, of medicine (hematology), and of pediatrics, was recently honored at Einstein’s 2014 Faculty Mentoring Awards ceremony for his contribution as a basic science mentor. He is also an attending physician in pediatrics at the Children’s Hospital at Montefiore.

 
 
 

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