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William R. Jacobs, Jr., Ph.D.

William R. Jacobs, Jr., Ph.D.

Professor, Microbiology & Immunology, Einstein

Professor, Genetics, Einstein

Leo and Julia Forchheimer Chair in Microbiology & Immunology, Einstein

Investigator, Howard Hughes Medical Institute (HHMI)

Infectious diseasesTuberculosis (TB)Vaccines

Molecular genetics

Dr. Jacobs is pioneering the use of molecular genetics to control tuberculosis (TB), which kills nearly two million people a year. His research is identifying the genes that make Mycobacterium  tuberculosis (MTB) - the bacteria that causes TB -  virulent, identifying new drug targets and engineering weakened strains that can be used as live vaccines. Dr. Jacobs was the first scientist to introduce foreign DNA into MTB, a technique now regularly used by TB investigators around the world. read more...

 

Liise-anne Pirofski, M.D.

Liise-anne Pirofski, M.D.

Professor, Medicine (Infectious Diseases), Einstein

Professor, Microbiology & Immunology, Einstein

Selma and Dr. Jacques Mitrani Chair in Biomedical Research, Einstein

Chief, Infectious Diseases, Department of Medicine, Einstein and Montefiore Health System

Infectious diseasesPneumoniaImmunology

Bacterial infectionsFungal infectionsVaccines

Dr. Pirofski studies innate and vaccine-induced immunity to disease-causing microbes, including Cryptococcus (the leading cause of fungal meningitis globally) and Pneumococcus (the leading cause of pneumonia in the United States and globally). She has described novel ways by which antibodies protect against bacterial pneumonia and sepsis and her work has improved understanding of how Cryptococcus and Pneumococcus cause disease. read more...